A new family of luminescent iridium complexes: synthesis, optical, and cytotoxic studies
By using N, N-dibutyl-2, 2′-bipyridine-4, 4′-dicarboxamide as a diimine (dbbpy) and
distinctive cyclometalated groups, this work reports a new family of cationic phosphorescent …
distinctive cyclometalated groups, this work reports a new family of cationic phosphorescent …
Design, synthesis and investigation of the mechanism of action underlying anti-leukemic effects of the quinolinequinones as LY83583 analogs
Literature conclusively shows that one of the quinolinequinone analogs (6-anilino-5, 8-
quinolinequinone), referred to as LY83583 hereafter, an inhibitor of guanylyl cyclase, was …
quinolinequinone), referred to as LY83583 hereafter, an inhibitor of guanylyl cyclase, was …
Luminescent cycloplatinated complexes with biologically relevant phosphine ligands: optical and cytotoxic properties
G Millán, N Giménez, R Lara, JR Berenguer… - Inorganic …, 2019 - ACS Publications
Two series of neutral luminescent pentafluorophenyl cycloplatinated (II) complexes [Pt (C^
N)(C6F5) L][C^ N= C-deprotonated 2-phenylpyridine (ppy; a), 2-(2, 4-difluorophenylpyridine …
N)(C6F5) L][C^ N= C-deprotonated 2-phenylpyridine (ppy; a), 2-(2, 4-difluorophenylpyridine …
Oleanolic acid dimers with potential application in medicine—Design, synthesis, physico-chemical characteristics, cytotoxic and antioxidant activity
The present work aimed to obtain a set of oleanolic acid derivatives with a high level of
cytotoxic and antioxidant activities and a low level of toxicity by applying an economical …
cytotoxic and antioxidant activities and a low level of toxicity by applying an economical …
Anti-tumor effects of novel alkannin derivatives with potent selectivity on comprehensive analysis
Z Dai, F Gao, Z Zhang, M Lu, Y Luo, T Zhang, B Shang… - Phytomedicine, 2023 - Elsevier
Background Therapeutic approaches based on glycolysis and energy metabolism of tumor
cells are new promising strategies for the treatment of cancer. Currently, researches on the …
cells are new promising strategies for the treatment of cancer. Currently, researches on the …
A novel series of chlorinated plastoquinone analogs: Design, synthesis, and evaluation of anticancer activity
Herein, we report the synthesis and cytotoxic effects of novel chlorinated plastoquinone
analogs (ABQ1–17) against different leukemic cells. Compounds ABQ3, ABQ11, and ABQ12 …
analogs (ABQ1–17) against different leukemic cells. Compounds ABQ3, ABQ11, and ABQ12 …
Screening for selective anticancer activity of 65 extracts of plants collected in Western Andalusia, Spain
JM Calderón-Montaño, SM Martínez-Sánchez… - Plants, 2021 - mdpi.com
Finding cytotoxic drugs with a high selectivity towards cancer cells is crucial to improve the
low survival rates of patients diagnosed with metastatic cancers. Since plants are an …
low survival rates of patients diagnosed with metastatic cancers. Since plants are an …
A new family of luminescent [Pt (pbt) 2 (C 6 F 5) L] n+ (n= 1, 0) complexes: synthesis, optical and cytotoxic studies
DG de Segura, N Giménez, D Rincón-Montón… - Dalton …, 2023 - pubs.rsc.org
Given the widely recognized bioactivity of 2-arylbenzothiazoles against tumor cells, we have
designed a new family of luminescent heteroleptic pentafluorophenyl-bis (2 …
designed a new family of luminescent heteroleptic pentafluorophenyl-bis (2 …
Discovery and structure–activity relationship of plastoquinone analogs as anticancer agents against chronic myelogenous leukemia cells
Abstract Two series of amino‐1, 4‐benzoquinones (AQ1–18) based on the structural
analogs of plastoquinones were synthesized and the structure–activity relationship against …
analogs of plastoquinones were synthesized and the structure–activity relationship against …
Aminated Quinolinequinones as Privileged Scaffolds for Antibacterial Agents: Synthesis, In Vitro Evaluation, and Putative Mode of Action
Our previous studies have revealed that the aminated 1, 4-quinone scaffold can be used for
the development of novel antibacterial and/or antifungal agents. In this study, the aminated …
the development of novel antibacterial and/or antifungal agents. In this study, the aminated …