The circadian rhythm is crucial for physiological and behavioral functions. Chronotype,
which represents individual preferences for activity and performance, is associated with …

Attention-deficit/hyperactivity disorder (ADHD) co-occurs with many other psychiatric
disorders and traits. In this review, we summarize and interpret the existing literature on the …

The circadian clock in mammals regulates the sleep/wake cycle and many associated
behavioral and physiological processes. The cellular clock mechanism involves a …

Attention-deficit/hyperactivity disorder (ADHD) is a common childhood-onset
neurodevelopmental disorder characterised by persistent inattention, hyperactivity and …

Circadian rhythm is an important mechanism that controls behavior and biochemical events
based on 24 h rhythmicity. Ample evidence indicates disturbance of this mechanism is …

Attention-deficit hyperactivity disorder (ADHD) is a highly heritable neurodevelopmental
disorder that affects approximately 5.3% of children and approximately 2.5% of adults. There …

Cryptochromes are negative transcriptional regulators of the circadian clock in mammals. It
is not clear how reducing the level of endogenous CRY1 in mammals will affect circadian …

The high overlapping nature of various features across multiple mental health disorders
suggests the existence of common psychopathology factor (s)(p-factors) that mediate similar …

The manifestations of chronic insomnia undergo age-related changes. In younger infants
and children, behavioral insomnia emerges as the most prevalent form and typically …

Regulatory agencies encourage computer modeling and simulation to reduce the time and
cost of clinical trials. Although still not classified in formal guidelines, system biology-based …