Effects of mesenchymal stem cell‐derived paracrine signals and their delivery strategies

C Chang, J Yan, Z Yao, C Zhang, X Li… - Advanced healthcare …, 2021 - Wiley Online Library
Mesenchymal stem cells (MSCs) have been widely studied as a versatile cell source for
tissue regeneration and remodeling due to their potent bioactivity, which includes …

[HTML][HTML] Neuroimmune signaling in alcohol use disorder

EK Erickson, EK Grantham, AS Warden… - Pharmacology …, 2019 - Elsevier
Alcohol use disorder (AUD) is a widespread disease with limited treatment options.
Targeting the neuroimmune system is a new avenue for developing or repurposing effective …

Biodistribution of mesenchymal stromal cells after administration in animal models and humans: a systematic review

M Sanchez-Diaz, MI Quiñones-Vico… - Journal of Clinical …, 2021 - mdpi.com
Mesenchymal Stromal Cells (MSCs) are of great interest in cellular therapy. Different routes
of administration of MSCs have been described both in pre-clinical and clinical reports …

Oxidative stress and neuroinflammation as a pivot in drug abuse. A focus on the therapeutic potential of antioxidant and anti-inflammatory agents and biomolecules

P Berríos-Cárcamo, M Quezada, ME Quintanilla… - Antioxidants, 2020 - mdpi.com
Drug abuse is a major global health and economic problem. However, there are no
pharmacological treatments to effectively reduce the compulsive use of most drugs of abuse …

Alcohol drinking patterns and laboratory indices of health: does type of alcohol preferred make a difference?

O Niemelä, M Aalto, A Bloigu, R Bloigu, AS Halkola… - Nutrients, 2022 - mdpi.com
Although excessive alcohol consumption is a highly prevalent public health problem the
data on the associations between alcohol consumption and health outcomes in individuals …

[HTML][HTML] Oleoylethanolamide, neuroinflammation, and alcohol abuse

L Orio, F Alen, FJ Pavón, A Serrano… - Frontiers in molecular …, 2019 - frontiersin.org
Neuroinflammation is a complex process involved in the physiophatology of many central
nervous system diseases, including addiction. Alcohol abuse is characterized by induction …

[HTML][HTML] Therapeutic effects of stem cells in different body systems, a novel method that is yet to gain trust: A comprehensive review

A Ebrahimi, H Ahmadi, ZP Ghasrodashti… - Bosnian journal of …, 2021 - ncbi.nlm.nih.gov
Stem cell therapy has been used to treat several types of diseases, and it is expected that its
therapeutic uses shall increase as novel lines of evidence begin to appear. Furthermore …

Epigenetics of alcohol use disorder—A review of recent advances in DNA methylation profiling

MJ Longley, J Lee, J Jung, FW Lohoff - Addiction biology, 2021 - Wiley Online Library
Alcohol use disorder (AUD) is a major contributor to morbidity and mortality worldwide.
Although there is a heritable component, the etiology of AUD is complex and can involve …

Immunosuppressive properties of cytochalasin B-induced membrane vesicles of mesenchymal stem cells: Comparing with extracellular vesicles derived from …

MO Gomzikova, AM Aimaletdinov, OV Bondar… - Scientific Reports, 2020 - nature.com
Extracellular vesicles derived from mesenchymal stem cells (MSCs) represent a novel
approach for regenerative and immunosuppressive therapy. Recently, cytochalasin B …

Aspirin and N‐acetylcysteine co‐administration markedly inhibit chronic ethanol intake and block relapse binge drinking: Role of neuroinflammation‐oxidative stress …

Y Israel, ME Quintanilla, F Ezquer, P Morales… - Addiction …, 2021 - Wiley Online Library
Chronic alcohol intake leads to neuroinflammation and cell injury, proposed to result in
alterations that perpetuate alcohol intake and cued relapse. Studies show that brain …