The roles of histone variants in fine-tuning chromatin organization and function
S Martire, LA Banaszynski - Nature reviews Molecular cell biology, 2020 - nature.com
Histones serve to both package and organize DNA within the nucleus. In addition to histone
post-translational modification and chromatin remodelling complexes, histone variants …
post-translational modification and chromatin remodelling complexes, histone variants …
Contribution of semen to early embryo development: fertilization and beyond
M Vallet-Buisan, R Mecca, C Jones… - Human …, 2023 - academic.oup.com
BACKGROUND It has long been thought that the factors affecting embryo and foetal
development were exclusively maternally derived; hence, if issues regarding fertility and …
development were exclusively maternally derived; hence, if issues regarding fertility and …
Histone variants and epigenetics
S Henikoff, MM Smith - Cold Spring Harbor perspectives …, 2015 - cshperspectives.cshlp.org
Histones package and compact DNA by assembling into nucleosome core particles. Most
histones are synthesized at S phase for rapid deposition behind replication forks. In addition …
histones are synthesized at S phase for rapid deposition behind replication forks. In addition …
[HTML][HTML] Chromatin dynamics during spermiogenesis
C Rathke, WM Baarends, S Awe… - Biochimica et Biophysica …, 2014 - Elsevier
The function of sperm is to safely transport the haploid paternal genome to the egg
containing the maternal genome. The subsequent fertilization leads to transmission of a new …
containing the maternal genome. The subsequent fertilization leads to transmission of a new …
Histone variants—ancient wrap artists of the epigenome
PB Talbert, S Henikoff - Nature reviews Molecular cell biology, 2010 - nature.com
Histones wrap DNA to form nucleosome particles that compact eukaryotic genomes. Variant
histones have evolved crucial roles in chromosome segregation, transcriptional regulation …
histones have evolved crucial roles in chromosome segregation, transcriptional regulation …
[HTML][HTML] Epigenetic regulation of the histone-to-protamine transition during spermiogenesis
J Bao, MT Bedford - Reproduction (Cambridge, England), 2016 - ncbi.nlm.nih.gov
In mammals, male germ cells differentiate from haploid round spermatids to flagella-
containing motile sperm, in a process called spermiogenesis. This process is distinct from …
containing motile sperm, in a process called spermiogenesis. This process is distinct from …
Every amino acid matters: essential contributions of histone variants to mammalian development and disease
I Maze, KM Noh, AA Soshnev, CD Allis - Nature Reviews Genetics, 2014 - nature.com
Despite a conserved role for histones as general DNA packaging agents, it is now clear that
another key function of these proteins is to confer variations in chromatin structure to ensure …
another key function of these proteins is to confer variations in chromatin structure to ensure …
[HTML][HTML] Essential role of histone replacement and modifications in male fertility
Spermiogenesis is a complex cellular differentiation process that the germ cells undergo a
distinct morphological change, and the protamines replace the core histones to facilitate …
distinct morphological change, and the protamines replace the core histones to facilitate …
[HTML][HTML] A decade of exploring the mammalian sperm epigenome: paternal epigenetic and transgenerational inheritance
A Champroux, J Cocquet, J Henry-Berger… - Frontiers in Cell and …, 2018 - frontiersin.org
The past decade has seen a tremendous increase in interest and progress in the field of
sperm epigenetics. Studies have shown that chromatin regulation during male germline …
sperm epigenetics. Studies have shown that chromatin regulation during male germline …
Histone H2A variants in nucleosomes and chromatin: more or less stable?
C Bönisch, SB Hake - Nucleic acids research, 2012 - academic.oup.com
In eukaryotes, DNA is organized together with histones and non-histone proteins into a
highly complex nucleoprotein structure called chromatin, with the nucleosome as its …
highly complex nucleoprotein structure called chromatin, with the nucleosome as its …