Alterations in hypothalamic–pituitary–adrenal (HPA) axis and its effector hormone cortisol
have been proposed as one possible mechanism linking child maltreatment experiences to …

Objective To summarize findings of previous studies on the prevalence of trauma and
Posttraumatic Stress Disorder (PTSD) in Conduct Disorder (CD). Method We conducted a …

Early-life adversity (ELA) is one of the major risk factors for serious mental and physical
health risks later in life. ELA has been associated with dysfunctional neurodevelopment …

BackgroundChildhood maltreatment is robustly associated with increased risk of poor
mental health outcome and changes in brain function. The authors investigated whether …

Childhood maltreatment is associated with alterations in neural architecture that potentially
put these children at increased risk for psychopathology. Alterations in white matter (WM) …

Maltreatment adversely impacts the development of children across a host of domains. One
way in which maltreatment may exert its deleterious effects is by becoming embedded in the …

Many children who experience childhood adversity, whether in the form of threat or
deprivation, develop adaptive competencies that lead to resilient functioning. Still, research …

Background: Previous studies have demonstrated that children who experience
maltreatment show a more elevated risk of psychopathological disorders than children from …

Childhood adversity has been associated with hypothalamic–pituitary–adrenal axis
dysregulation, which is associated with mental and physical health consequences …

This review argues for a central role of the lateral hypothalamus in those deviant forms of
aggression, which result from chronic glucocorticoid deficiency. Currently, this nucleus is …