Introduction The safety of arterial hyperoxia is under increasing scrutiny. We performed a
systematic review of the literature to determine whether any association exists between …

This review surveys the efforts taken to achieve clinically efficacious protection of the
ischemic brain and underscores the necessity of expanding our purview to include the …

Objective In this retrospective multi-centre cohort study, we tested the hypothesis that
hyperoxia was not associated with higher in-hospital case fatality in ventilated traumatic …

Traumatic brain injury (TBI) is a major public health issue. The complexity of TBI has
precluded the use of effective therapies. Hyperbaric oxygen therapy (HBOT) has been …

Background Normobaric oxygen therapy is frequently applied in neurocritical care, however,
whether supplemental FiO 2 has beneficial cerebral effects is still controversial. We …

Introduction The relationship between hyperoxemia and outcome in patients with traumatic
brain injury (TBI) is controversial. We sought to investigate the independent relationship …

Traumatic Brain Injury (TBI) remains a significant cause of mortality and morbidity, affecting
individuals of all age groups. Much remains to be learned about its complex …

Stroke, one of the most debilitating cerebrovascular and nuerological diseases, is a serious
life-threatening condition and a leading cause of long-term adult disability and brain …

Michalski D, Härtig W, Schneider D, Hobohm C. Use of normobaric and hyperbaric oxygen
in acute focal cerebral ischemia–a preclinical and clinical review. Acta Neurol Scand: 2011 …

In addition to immunological and wound healing cell and platelet delivery, ion stasis and
nutrient supply, blood delivers oxygen to cells and tissues and removes metabolic wastes …