Review of alternatives to antibiotic use in aquaculture

MG Bondad‐Reantaso, B MacKinnon… - Reviews in …, 2023 - Wiley Online Library
With the rapid growth of the aquaculture production since the 1980s, there has been a
concomitant increase in disease outbreaks. The injudicious and/or incorrect use of …

Phage therapy in the postantibiotic era

FL Gordillo Altamirano, JJ Barr - Clinical microbiology reviews, 2019 - Am Soc Microbiol
Antibiotic resistance is arguably the biggest current threat to global health. An increasing
number of infections are becoming harder or almost impossible to treat, carrying high …

The safety and toxicity of phage therapy: a review of animal and clinical studies

D Liu, JD Van Belleghem, CR de Vries, E Burgener… - Viruses, 2021 - mdpi.com
Increasing rates of infection by antibiotic resistant bacteria have led to a resurgence of
interest in bacteriophage (phage) therapy. Several phage therapy studies in animals and …

Abortive infection: bacterial suicide as an antiviral immune strategy

A Lopatina, N Tal, R Sorek - Annual review of virology, 2020 - annualreviews.org
Facing frequent phage challenges, bacteria have evolved numerous mechanisms to resist
phage infection. A commonly used phage resistance strategy is abortive infection (Abi), in …

Gut microbiota and colonization resistance against bacterial enteric infection

QR Ducarmon, RD Zwittink, BVH Hornung… - Microbiology and …, 2019 - Am Soc Microbiol
The gut microbiome is critical in providing resistance against colonization by exogenous
microorganisms. The mechanisms via which the gut microbiota provide colonization …

Bacteriophage therapy: clinical trials and regulatory hurdles

LL Furfaro, MS Payne, BJ Chang - Frontiers in cellular and infection …, 2018 - frontiersin.org
Increasing reports of antimicrobial resistance and limited new antibiotic discoveries and
development have fuelled innovation in other research fields and led to a revitalization of …

Systematic exploration of Escherichia coli phage–host interactions with the BASEL phage collection

E Maffei, A Shaidullina, M Burkolter, Y Heyer… - PLoS …, 2021 - journals.plos.org
Bacteriophages, the viruses infecting bacteria, hold great potential for the treatment of
multidrug-resistant bacterial infections and other applications due to their unparalleled …

Phage-antibiotic synergy is driven by a unique combination of antibacterial mechanism of action and stoichiometry

C Gu Liu, SI Green, L Min, JR Clark, KC Salazar… - MBio, 2020 - Am Soc Microbiol
The continued rise in antibiotic resistance is precipitating a medical crisis. Bacteriophage
(phage) has been hailed as one possible therapeutic option to augment the efficacy of …

Bacteriophage therapy as an alternative treatment for human infections. A comprehensive review

A Kakasis, G Panitsa - International journal of antimicrobial agents, 2019 - Elsevier
Bacteriophages, or phages, are viruses that infect bacteria. They were discovered around a
century ago and have been used ever since for therapeutic purposes, particularly in former …

Evolutionary pathways and trajectories in antibiotic resistance

F Baquero, JL Martinez, V F. Lanza… - Clinical Microbiology …, 2021 - Am Soc Microbiol
Evolution is the hallmark of life. Descriptions of the evolution of microorganisms have
provided a wealth of information, but knowledge regarding “what happened” has precluded …