Super-resolution imaging techniques that overcome the diffraction limit of light have gained
wide popularity for visualizing cellular structures with nanometric resolution. Following the …

Super-resolution microscopy (SRM) bypasses the diffraction limit, a physical barrier that
restricts the optical resolution to roughly 250 nm and was previously thought to be …

Fluorescence nanoscopy uniquely combines minimally invasive optical access to the
internal nanoscale structure and dynamics of cells and tissues with molecular detection …

Stimulated emission depletion (STED) microscopy provides subdiffraction resolution while
preserving useful aspects of fluorescence microscopy, such as optical sectioning, and …

Many biological investigations require 3D imaging of cells or tissues with nanoscale spatial
resolution. We recently discovered that preserved biological specimens can be physically …

We introduce far-red, fluorogenic probes that combine minimal cytotoxicity with excellent
brightness and photostability for fluorescence imaging of actin and tubulin in living cells …

Actin and spectrin play important roles in neurons, but their organization in axons and
dendrites remains unclear. We used stochastic optical reconstruction microscopy to study …

The extracellular space (ECS) of the brain has an extremely complex spatial organization,
which has defied conventional light microscopy. Consequently, despite a marked interest in …

The structure of neuronal circuits that subserve cognitive functions in the brain is shaped
and refined throughout development and into adulthood. Evidence from human and animal …

Far-field optical microscopy using focused light is an important tool in a number of scientific
disciplines including chemical,(bio) physical and biomedical research, particularly with …