Aim Symptoms of bipolar disorder (BD) include changes in mood, activity, energy, sleep,
and appetite. Since many of these processes are regulated by circadian function, circadian …

Exposure to light affects our physiology and behaviour through a pathway connecting the
retina to the circadian pacemaker in the hypothalamus–the suprachiasmatic nucleus (SCN) …

A variety of psychological and physical phenomena elicit variations in the diameter of pupil
of the eye. Changes in pupil size are mediated by the relative activation of the sphincter …

Introduction Despite the growing number of different therapeutic options, treatment of
depression is still a challenge. A broader perspective reveals the benefits of bright light …

Sleep and circadian rhythm disruptions are symptoms of, and hypothesized underlying
mechanisms in, seasonal depression. Discrepant observational findings and mixed …

Adaptation of physiology and behavior to seasonal changes in the environment are for many
organisms essential for survival. Most of our knowledge about the underlying mechanisms …

Background Numerous studies have reported that eveningness is associated with increased
alcohol consumption. However, biological markers of circadian timing, such as dim light …

Background Late-life depression (LLD) is a prevalent neuropsychiatric disorder in the older
population. While LLD exhibits high mortality rates, depressive symptoms in older adults are …

Study Objectives Altered light sensitivity may be an underlying vulnerability for disrupted
circadian photoentrainment. The photic information necessary for circadian …

Background This study is a confirmatory efficacy trial of two treatments for winter seasonal
affective disorder (SAD): SAD-tailored group cognitive-behavioral therapy (CBT-SAD) and …