Background Cardiovascular disease is the main cause of death in the United States, with
smoking being the primary preventable cause of premature death, and thrombosis being the …

Background & Aims Cigarette smoking is a major risk factor for pancreatic cancer.
Aggressive pancreatic tumors contain cancer cells with stem cell features. We investigated …

Pre-clinical studies investigated the effects of chronic exposure to nicotine on lungs, kidneys
and brains using animal models. Most of these studies delivered nicotine into the circulatory …

Nicotine is a highly addictive compound present in tobacco, which causes the release of
dopamine in different regions of the brain. Recent studies have shown that astrocytes …

In recent years, tobacco smoking is a risk factor for a series of diseases, including
cardiovascular diseases, cerebrovascular diseases, and cancers. Nicotine, the primary …

Despite the protective nature of the blood-brain barrier (BBB) and brain-protecting tissues,
some types of CNS injury or stress can cause cerebral cytokine production and profound …

Nicotine use is a leading cause of preventable deaths worldwide, and most of those who
attempt to quit will relapse. While electronic cigarettes and other electronic nicotine delivery …

Electronic nicotine delivery systems (ENDS), also commonly known as electronic cigarettes
(e-cigs) are considered in most cases as a safer alternative to tobacco smoking and …

It is well established that tobacco smoking is associated with vascular endothelial
dysfunction in a causative and dose dependent manner primarily related to the tobacco …

It has been shown that prenatal nicotine and tobacco smoke exposure can cause different
neurobehavioral disorders in the offspring. We hypothesize that prenatal exposure to …