Extracellular vesicles (EVs), such as exosomes or oncosomes, often carry oncogenic
molecules derived from tumor cells. In addition, accumulating evidence indicates that tumor …

Spinal cord injury (SCI) is a devastating condition with no curative therapy currently
available. Immunomodulation can be applied as a therapeutic strategy to drive alternative …

Central nervous system (CNS) trauma is a prominent cause of mortality and morbidity, and
although much effort has focused on developing treatments for CNS trauma–related …

Although limited spontaneous recovery occurs after spinal cord injury (SCI), current
knowledge reveals that multiple forms of axon growth in spared axons can lead to circuit …

Cryopreservation of adherent cells is crucial for commercial cell therapy technology,
including effective distribution and storage. Fast thawing has been shown to increase cell …

Ex vivo spinal cord slice cultures (SCSC) allow study of spinal cord circuitry, maintaining
stimuli responses comparable to live animals. Previously, we have shown that mesenchymal …

Neurodegeneration is a catastrophic process that develops progressive damage leading to
functional and structural loss of the cells of the nervous system and is among the biggest …

The failure of the spinal cord to regenerate can be attributed both to a lack of trophic support
for regenerating axons and to upregulation of inhibitory factors such as chondroitin sulphate …

The influence of glucagon-like peptide-1 (GLP-1) on CNS functions, such as neurogenesis,
neuroprotection, and anti-neuroinflammation, prompted investigation into its role in spinal …

Background: Spinal cord injury (SCI) induces distal effects on neural activity in the brain. To
date, precise, high quality anatomical studies have not been performed. The goal of this …