Anti-PD-1 therapy is used as a front-line treatment for many cancers, but mechanistic insight
into this therapy resistance is still lacking. Here we generate a humanized (Hu)-mouse …

Multidrug-resistant (MDR) superbugs can breach the blood–brain barrier (BBB), leading to a
continuous barrage of pro-inflammatory modulators and induction of severe infection-related …

Cystic fibrosis (CF) pathophysiology is hallmarked by excessive inflammation and the
inability to efficiently resolve lung infections, contributing to morbidly and eventually the …

Alveolar macrophages (AMs) reside on the luminal surface of the airways and alveoli,
ensuring proper gas exchange by ingesting cellular debris and pathogens, and regulating …

Extracellular vesicles (EVs) are nanoscale membrane-enveloped vesicles secreted by
prokaryotic and eukaryotic cells, which are commonly defined as membrane vesicles (MVs) …

Extracellular vesicles (EVs) act as cell communicators and immune response modulators
and may be employed as disease biomarkers and drug delivery systems. In infectious …

Infectious diseases are the leading cause of death in both adults and children, with
respiratory infections being the leading cause of death. A growing body of evidence …

Pseudomonas aeruginosa keratitis occurs following trauma, in immunocompromised
patients, and in otherwise healthy contact lens wearers. Characterized by a light-blocking …

This work is dedicated to the characterization by Atomic Force Microscopy (AFM) of
Pseudomonas fluorescens, bacteria having high potential in biotechnology. They were first …

Epigenetics describes chemical modifications of the genome that do not alter DNA
sequence but participate in the regulation of gene expression and cellular processes such …