Tumor-infiltrating mast cells are associated with resistance to anti-PD-1 therapy
R Somasundaram, T Connelly, R Choi, H Choi… - Nature …, 2021 - nature.com
Anti-PD-1 therapy is used as a front-line treatment for many cancers, but mechanistic insight
into this therapy resistance is still lacking. Here we generate a humanized (Hu)-mouse …
into this therapy resistance is still lacking. Here we generate a humanized (Hu)-mouse …
Membrane vesicles derived from gut microbiota and probiotics: Cutting-edge therapeutic approaches for multidrug-resistant superbugs linked to neurological …
P Srivastava, K Kim - Pharmaceutics, 2022 - mdpi.com
Multidrug-resistant (MDR) superbugs can breach the blood–brain barrier (BBB), leading to a
continuous barrage of pro-inflammatory modulators and induction of severe infection-related …
continuous barrage of pro-inflammatory modulators and induction of severe infection-related …
[PDF][PDF] Update on innate and adaptive immunity in cystic fibrosis
EM Bruscia, TL Bonfield - Clinics in Chest Medicine, 2022 - Elsevier
Cystic fibrosis (CF) pathophysiology is hallmarked by excessive inflammation and the
inability to efficiently resolve lung infections, contributing to morbidly and eventually the …
inability to efficiently resolve lung infections, contributing to morbidly and eventually the …
ScRNA-seq expression of IFI27 and APOC2 identifies four alveolar macrophage superclusters in healthy BALF
X Li, FW Kolling, D Aridgides, D Mellinger… - Life science …, 2022 - life-science-alliance.org
Alveolar macrophages (AMs) reside on the luminal surface of the airways and alveoli,
ensuring proper gas exchange by ingesting cellular debris and pathogens, and regulating …
ensuring proper gas exchange by ingesting cellular debris and pathogens, and regulating …
[HTML][HTML] Extracellular vesicle-mediated regulation of macrophage polarization in bacterial infections
M Qu, H Zhu, X Zhang - Frontiers in Microbiology, 2022 - frontiersin.org
Extracellular vesicles (EVs) are nanoscale membrane-enveloped vesicles secreted by
prokaryotic and eukaryotic cells, which are commonly defined as membrane vesicles (MVs) …
prokaryotic and eukaryotic cells, which are commonly defined as membrane vesicles (MVs) …
[HTML][HTML] Extracellular vesicles: potential role in remote signaling and inflammation in Trypanosoma cruzi-triggered disease
L Dantas-Pereira, R Menna-Barreto… - Frontiers in Cell and …, 2021 - frontiersin.org
Extracellular vesicles (EVs) act as cell communicators and immune response modulators
and may be employed as disease biomarkers and drug delivery systems. In infectious …
and may be employed as disease biomarkers and drug delivery systems. In infectious …
[HTML][HTML] Outer membrane vesicles from bacteria: Role and potential value in the pathogenesis of chronic respiratory diseases
F Han, W Wang, M Shi, H Zhou, Y Yao, C Li… - Frontiers in Cellular …, 2022 - frontiersin.org
Infectious diseases are the leading cause of death in both adults and children, with
respiratory infections being the leading cause of death. A growing body of evidence …
respiratory infections being the leading cause of death. A growing body of evidence …
Pseudomonas aeruginosa-Derived Extracellular Vesicles Modulate Corneal Inflammation: Role in Microbial Keratitis?
R Ayilam Ramachandran, A Lemoff… - Infection and …, 2023 - Am Soc Microbiol
Pseudomonas aeruginosa keratitis occurs following trauma, in immunocompromised
patients, and in otherwise healthy contact lens wearers. Characterized by a light-blocking …
patients, and in otherwise healthy contact lens wearers. Characterized by a light-blocking …
Impact of Growth Conditions on Pseudomonas fluorescens Morphology Characterized by Atomic Force Microscopy
This work is dedicated to the characterization by Atomic Force Microscopy (AFM) of
Pseudomonas fluorescens, bacteria having high potential in biotechnology. They were first …
Pseudomonas fluorescens, bacteria having high potential in biotechnology. They were first …
To target or not to target? The role of DNA and histone methylation in bacterial infections
M Barbachowska, PB Arimondo - Epigenetics, 2023 - Taylor & Francis
Epigenetics describes chemical modifications of the genome that do not alter DNA
sequence but participate in the regulation of gene expression and cellular processes such …
sequence but participate in the regulation of gene expression and cellular processes such …