[HTML][HTML] Brain-derived neurotrophic factor signaling in depression and antidepressant action
E Castrén, LM Monteggia - Biological psychiatry, 2021 - Elsevier
Neurotrophic factors, particularly BDNF (brain-derived neurotrophic factor), have been
associated with depression and antidepressant drug action. A variety of preclinical and …
associated with depression and antidepressant drug action. A variety of preclinical and …
Stress, epigenetics and depression: a systematic review
Environmental stressors, such as childhood maltreatment, have been recognized to
contribute to the development of depression. Growing evidence suggests that epigenetic …
contribute to the development of depression. Growing evidence suggests that epigenetic …
[HTML][HTML] Understanding the complex of suicide in depression: from research to clinics
L Orsolini, R Latini, M Pompili, G Serafini… - Psychiatry …, 2020 - ncbi.nlm.nih.gov
Objective Amongst psychiatric disorders, major depressive disorder (MDD) is the most
prevalent, by affecting approximately 15–17% of the population and showing a high suicide …
prevalent, by affecting approximately 15–17% of the population and showing a high suicide …
Dissecting early life stress-induced adolescent depression through epigenomic approach
S Ochi, Y Dwivedi - Molecular psychiatry, 2023 - nature.com
Early life stress (ELS), such as abuse and neglect during childhood, can lead to psychiatric
disorders in later life. Previous studies have suggested that ELS can cause profound …
disorders in later life. Previous studies have suggested that ELS can cause profound …
The FKBP51 glucocorticoid receptor co-chaperone: regulation, function, and implications in health and disease
Among the chaperones and co-chaperones regulating the glucocorticoid receptor (GR),
FK506 binding protein (FKBP) 51 is the most intensely investigated across different …
FK506 binding protein (FKBP) 51 is the most intensely investigated across different …
A comprehensive review of genetic and epigenetic mechanisms that regulate BDNF expression and function with relevance to major depressive disorder
Major depressive disorder (MDD) is a mood disorder that affects behavior and impairs
cognition. A gene potentially important to this disorder is the brain derived neurotrophic …
cognition. A gene potentially important to this disorder is the brain derived neurotrophic …
Gene expression studies in Depression development and treatment: an overview of the underlying molecular mechanisms and biological processes to identify …
N Mariani, N Cattane, C Pariante, A Cattaneo - Translational psychiatry, 2021 - nature.com
A combination of different risk factors, such as genetic, environmental and psychological
factors, together with immune system, stress response, brain neuroplasticity and the …
factors, together with immune system, stress response, brain neuroplasticity and the …
Advance in stress for depressive disorder
Y Ding, J Dai - Depressive Disorders: Mechanisms, Measurement and …, 2019 - Springer
Stress is an adaptive response to environment aversive stimuli and a common life
experience of one's daily life. Chronic or excessive stress especially that happened in early …
experience of one's daily life. Chronic or excessive stress especially that happened in early …
Glucocorticoid receptor gene (NR3C1) DNA methylation in association with trauma, psychopathology, transcript expression, or genotypic variation: A systematic …
OJ Watkeys, K Kremerskothen, Y Quide… - Neuroscience & …, 2018 - Elsevier
The glucocorticoid receptor gene (NR3C1) is a critical component of the stress response
system. Cytosine methylation of NR3C1 has been repeatedly associated with trauma and …
system. Cytosine methylation of NR3C1 has been repeatedly associated with trauma and …
[HTML][HTML] Major depressive disorder with suicidal ideation or behavior in Chinese population: A scoping review of current evidence on disease assessment, burden …
C Ye, Q Xin, T Si - Journal of affective disorders, 2023 - Elsevier
Background Identifying and managing major depressive disorder (MDD) patients with
suicidal ideation or behavior (MDSI) is critical for reducing the disease burden. This scoping …
suicidal ideation or behavior (MDSI) is critical for reducing the disease burden. This scoping …