The engineering of fully functional, biological‐like tissues requires biomaterials to direct
cellular events to a near‐native, 3D niche extent. Natural biomaterials are generally seen as …

Abstract Treatment of critical-size bone defects is a major medical challenge since neither
the bone tissue can regenerate nor current regenerative approaches are effective. Emerging …

Platelet-rich plasma (PRP) and its derivatives have been investigated and applied in
regenerative medicine. The use of PRP as a supplement of cell culture media has …

The restoration of dentine-pulp complex remains a challenge for dentists; nonetheless, it has
been poorly addressed. An ideal system should modulate the host response, as well as …

Blood components play key roles in the modulation of the wound healing process and,
together with the provisional fibrin matrix ability to selectively bind bioactive molecules and …

Wound healing is one of the most complex processes that our bodies must perform. While
our ability to repair wounds is often taken for granted, conditions such as diabetes, obesity …

Abstract 3D cell culture platforms have emerged as a setting that resembles in vivo
environments replacing the traditional 2D platforms. Over the recent years, an extensive …

Background Mesenchymal stem cells are a promising cell source for chondrogenic
differentiation and have been widely used in several preclinical and clinical studies …

Abstract Three-dimensional (3D) printing shows potential for use as an advanced
technology for forming biomimetic tissue and other complex structures. However, there are …

One of the promising approaches to facilitate healing and regenerative capacity includes the
application of growth-factor-loaded biomaterials. Human platelet lysate (hPL) derived from …