Antimicrobial peptides: A new hope in biomedical and pharmaceutical fields

A Moretta, C Scieuzo, AM Petrone, R Salvia… - Frontiers in cellular …, 2021 - frontiersin.org
Antibiotics are essential drugs used to treat pathogenic bacteria, but their prolonged use
contributes to the development and spread of drug-resistant microorganisms. Antibiotic …

Antibiofilm activity of host defence peptides: complexity provides opportunities

REW Hancock, MA Alford, EF Haney - Nature Reviews Microbiology, 2021 - nature.com
Host defence peptides (HDPs) are integral components of innate immunity across all living
organisms. These peptides can exert direct antibacterial effects, targeting planktonic cells …

Insect antimicrobial peptides: potential weapons to counteract the antibiotic resistance

MD Manniello, A Moretta, R Salvia, C Scieuzo… - Cellular and Molecular …, 2021 - Springer
Misuse and overuse of antibiotics have contributed in the last decades to a phenomenon
known as antibiotic resistance which is currently considered one of the principal threats to …

A bioinformatic study of antimicrobial peptides identified in the Black Soldier Fly (BSF) Hermetia illucens (Diptera: Stratiomyidae)

A Moretta, R Salvia, C Scieuzo, A Di Somma, H Vogel… - Scientific reports, 2020 - nature.com
Antimicrobial peptides (AMPs) play a key role in the innate immunity, the first line of defense
against bacteria, fungi, and viruses. AMPs are small molecules, ranging from 10 to 100 …

Antimicrobial mechanisms and clinical application prospects of antimicrobial peptides

X Li, S Zuo, B Wang, K Zhang, Y Wang - Molecules, 2022 - mdpi.com
Antimicrobial peptides are a type of small-molecule peptide that widely exist in nature and
are components of the innate immunity of almost all living things. They play an important role …

Antimicrobial and antibiofilm peptides

A Di Somma, A Moretta, C Canè, A Cirillo, A Duilio - Biomolecules, 2020 - mdpi.com
The increasing onset of multidrug-resistant bacteria has propelled microbiology research
towards antimicrobial peptides as new possible antibiotics from natural sources …

Novel approaches to combat medical device-associated biofilms

X Li, L Sun, P Zhang, Y Wang - Coatings, 2021 - mdpi.com
Biofilms are aggregates formed as a protective survival state by microorganisms to adapt to
the environment and can be resistant to antimicrobial agents and host immune responses …

Plant derived antimicrobial peptides: Mechanism of target, isolation techniques, sources and pharmaceutical applications

P Sharma, J Kaur, G Sharma… - Journal of Food …, 2022 - Wiley Online Library
Antimicrobial resistance is a global health and development threat which is caused by the
excess and prolonged usage of antimicrobial compounds in agriculture and pharmaceutical …

First-in-class cyclic Temporin L analogue: Design, synthesis, and antimicrobial assessment

R Bellavita, B Casciaro, S Di Maro… - Journal of medicinal …, 2021 - ACS Publications
The pharmacodynamic and pharmacokinetic properties of bioactive peptides can be
modulated by introducing conformational constraints such as intramolecular …

Structural and Functional Characterization of a Novel Recombinant Antimicrobial Peptide from Hermetia illucens

A Di Somma, A Moretta, C Cané, C Scieuzo… - Current Issues in …, 2021 - mdpi.com
Antibiotics are commonly used to treat pathogenic bacteria, but their prolonged use
contributes to the development and spread of drug-resistant microorganisms raising the …