The healthy human virome: from virus–host symbiosis to disease
Viruses are ubiquitous, essential components of any ecosystem, and of multicellular
organism holobionts. Numerous viruses cause acute infection, killing the host or being …
organism holobionts. Numerous viruses cause acute infection, killing the host or being …
Why the HIV reservoir never runs dry: clonal expansion and the characteristics of HIV-infected cells challenge strategies to cure and control HIV infection
CY Lau, MA Adan, F Maldarelli - Viruses, 2021 - mdpi.com
Antiretroviral therapy (ART) effectively reduces cycles of viral replication but does not target
proviral populations in cells that persist for prolonged periods and that can undergo clonal …
proviral populations in cells that persist for prolonged periods and that can undergo clonal …
Activation of endogenous retrovirus triggers microglial immuno-inflammation and contributes to negative emotional behaviors in mice with chronic stress
H Bao, J Yan, J Huang, W Deng, C Zhang, C Liu… - Journal of …, 2023 - Springer
Background The “missing” link of complex and multifaceted interplay among endogenous
retroviruses (ERVs) transcription, chronic immuno-inflammation, and the development of …
retroviruses (ERVs) transcription, chronic immuno-inflammation, and the development of …
An old model with new insights: endogenous retroviruses drive the evolvement toward ASD susceptibility and hijack transcription machinery during development
CW Lin, J Ellegood, K Tamada, I Miura, M Konda… - Molecular …, 2023 - nature.com
Abstract The BTBR T+ Itpr3 tf/J (BTBR/J) strain is one of the most valid models of idiopathic
autism, serving as a potent forward genetics tool to dissect the complexity of autism. We …
autism, serving as a potent forward genetics tool to dissect the complexity of autism. We …
GWAS reveals determinants of mobilization rate and dynamics of an active endogenous retrovirus of cattle
Five to ten percent of mammalian genomes is occupied by multiple clades of endogenous
retroviruses (ERVs), that may count thousands of members. New ERV clades arise by …
retroviruses (ERVs), that may count thousands of members. New ERV clades arise by …
Modulation of HERV expression by four different encephalitic arboviruses during infection of human primary astrocytes
FL Castro, OJB Brustolini, VEV Geddes, JPBM Souza… - Viruses, 2022 - mdpi.com
Human retroelements (HERVs) are retroviral origin sequences fixed in the human genome.
HERVs induction is associated with neurogenesis, cellular development, immune activation …
HERVs induction is associated with neurogenesis, cellular development, immune activation …
Regulation of endogenous retroviruses in murine embryonic stem cells and early embryos
X Lu - Journal of Molecular Cell Biology, 2023 - academic.oup.com
Endogenous retroviruses (ERVs) are important components of transposable elements that
constitute∼ 40% of the mouse genome. ERVs exhibit dynamic expression patterns during …
constitute∼ 40% of the mouse genome. ERVs exhibit dynamic expression patterns during …
Human endogenous retroviruses and toll-like receptors
X Jin, X Li, F Guan, J Zhang - Viral Immunology, 2023 - liebertpub.com
Human endogenous retroviruses (HERVs) are estimated to comprise∼ 8% of the entire
human genome, but the vast majority of them remain transcriptionally silent in most normal …
human genome, but the vast majority of them remain transcriptionally silent in most normal …
[HTML][HTML] Human Endogenous Retroviruses and Their Putative Role in Pathogenesis of Alzheimer's Disease, Inflammation, and Senescence
P Kozubek, J Kuźniar, M Czaja, H Sitka, U Kochman… - Biomedicines, 2024 - mdpi.com
The human endogenous retroviruses (HERVs) are ancient exogenous retroviruses that were
embedded in the germline over 30 million years ago and underwent an endogenization …
embedded in the germline over 30 million years ago and underwent an endogenization …
What role do endogenous retroviruses play in domestic cats infected with feline leukaemia virus?
MC Canto-Valdés, ME Bolio González… - New Zealand …, 2023 - Taylor & Francis
Feline leukaemia virus (FeLV) is a retrovirus that infects domestic and wild cats around the
world. FeLV infection is associated with the development of neoplasms, bone marrow …
world. FeLV infection is associated with the development of neoplasms, bone marrow …