[HTML][HTML] Structure and function: Lipid A modifications in commensals and pathogens

A Steimle, IB Autenrieth, JS Frick - International Journal of Medical …, 2016 - Elsevier
Lipopolysaccharides (LPS) of Gram negative bacteria are one of the most potent stimulators
of the host innate immune system and LPS recognition is essential for the host organism to …

The structures of core regions from enterobacterial lipopolysaccharides–an update

O Holst - FEMS microbiology letters, 2007 - academic.oup.com
To the major virulence factors of Gram-negative bacteria belong the lipopolysaccharides
(endotoxins), which are very well characterized for their immunological, pharmacological …

[PDF][PDF] The NLRP12 inflammasome recognizes Yersinia pestis

GI Vladimer, D Weng, SWM Paquette, SK Vanaja… - Immunity, 2012 - cell.com
Yersinia pestis, the causative agent of plague, is able to suppress production of
inflammatory cytokines IL-18 and IL-1β, which are generated through caspase-1-activating …

Virulence factors of Yersinia pestis are overcome by a strong lipopolysaccharide response

SW Montminy, N Khan, S McGrath, MJ Walkowicz… - Nature …, 2006 - nature.com
At mammalian body temperature, the plague bacillus Yersinia pestis synthesizes
lipopolysaccharide (LPS)–lipid A with poor Toll-like receptor 4 (TLR4)–stimulating activity …

Lipopolysaccharide inner core oligosaccharide structure and outer membrane stability in human pathogens belonging to the Enterobacteriaceae

E Frirdich, C Whitfield - Journal of endotoxin research, 2005 - journals.sagepub.com
In the Enterobacteriaceae, the outer membrane is primarily comprised of
lipopolysaccharides. The lipopolysaccharide molecule is important in mediating interactions …

Redefining the Requisite Lipopolysaccharide Structure in Escherichia coli

TC Meredith, P Aggarwal, U Mamat… - ACS chemical …, 2006 - ACS Publications
Gram-negative bacteria possess an asymmetric lipid bilayer surrounding the cell wall, the
outer membrane (OM). The OM inner leaflet is primarily composed of various …

From bench to bedside: stealth of enteroinvasive pathogens

RM Tsolis, GM Young, JV Solnick… - Nature Reviews …, 2008 - nature.com
Bacterial enteric infections are often associated with diarrhoea or vomiting, which are clinical
presentations commonly referred to as gastroenteritis. However, some enteric pathogens …

Structural characterization of bacterial lipopolysaccharides with mass spectrometry and on‐and off‐line separation techniques

A Kilár, Á Dörnyei, B Kocsis - Mass spectrometry reviews, 2013 - Wiley Online Library
The focus of this review is the application of mass spectrometry to the structural
characterization of bacterial lipopolysaccharides (LPSs), also referred to as “endotoxins,” …

Invited review: breaking barriers—attack on innate immune defences by omptin surface proteases of enterobacterial pathogens

J Haiko, M Suomalainen, T Ojala… - Innate …, 2009 - journals.sagepub.com
The omptin family of Gram-negative bacterial transmembrane aspartic proteases comprises
surface proteins with a highly conserved β-barrel fold but differing biological functions. The …

Identification of the lipopolysaccharide core of Yersinia pestis and Yersinia pseudotuberculosis as the receptor for bacteriophage φA1122

S Kiljunen, N Datta, SV Dentovskaya… - Journal of …, 2011 - Am Soc Microbiol
ABSTRACT φA1122 is a T7-related bacteriophage infecting most isolates of Yersinia pestis,
the etiologic agent of plague, and used by the CDC in the identification of Y. pestis. φA1122 …