[HTML][HTML] Small molecule-based treatment approaches for intervertebral disc degeneration: current options and future directions
Low back pain (LBP) is a major reason for disability, and symptomatic intervertebral disc
(IVD) degeneration (IDD) contributes to roughly 40% of all LBP cases. Current treatment …
(IVD) degeneration (IDD) contributes to roughly 40% of all LBP cases. Current treatment …
Recent progress in the structural modification of chitosan for applications in diversified biomedical fields
This article critically reviews the recent developments in the structural modifications of
chitosan and its nano-structured variants produced via different techniques and their …
chitosan and its nano-structured variants produced via different techniques and their …
Intervertebral disc degeneration—Current therapeutic options and challenges
Degeneration of the intervertebral disc (IVD) is a normal part of aging. Due to the spine's
declining function and the development of pain, it may affect one's physical health, mental …
declining function and the development of pain, it may affect one's physical health, mental …
[HTML][HTML] Progress in regulating inflammatory biomaterials for intervertebral disc regeneration
H Xiang, W Zhao, K Jiang, J He, L Chen, W Cui, Y Li - Bioactive Materials, 2024 - Elsevier
Intervertebral disc degeneration (IVDD) is rising worldwide and leading to significant health
issues and financial strain for patients. Traditional treatments for IVDD can alleviate pain but …
issues and financial strain for patients. Traditional treatments for IVDD can alleviate pain but …
Layered double hydroxides: a novel promising 2D nanomaterial for bone diseases treatment
Bone diseases including bone defects, bone infections, osteoarthritis, and bone tumors
seriously affect life quality of the patient and bring serious economic burdens to social health …
seriously affect life quality of the patient and bring serious economic burdens to social health …
Innovative strategies for intervertebral disc regenerative medicine: from cell therapies to multiscale delivery systems
As our understanding of the physiopathology of intervertebral disc (IVD) degeneration has
improved, novel therapeutic strategies have emerged, based on the local injection of cells …
improved, novel therapeutic strategies have emerged, based on the local injection of cells …
An update on animal models of intervertebral disc degeneration and low back pain: exploring the potential of artificial intelligence to improve research analysis and …
Animal models have been invaluable in the identification of molecular events occurring in
and contributing to intervertebral disc (IVD) degeneration and important therapeutic targets …
and contributing to intervertebral disc (IVD) degeneration and important therapeutic targets …
Layered double hydroxide nanoparticles with osteogenic effects as miRNA carriers to synergistically promote osteogenesis of MSCs
L Yang, X He, G Jing, H Wang, J Niu… - … Applied Materials & …, 2021 - ACS Publications
Inefficient differentiation and poor engraftment hinder the clinical applications of
mesenchymal stem cell (MSC)-based cell therapies in regenerative medicine. Layered …
mesenchymal stem cell (MSC)-based cell therapies in regenerative medicine. Layered …
[HTML][HTML] Drug delivery in intervertebral disc degeneration and osteoarthritis: Selecting the optimal platform for the delivery of disease-modifying agents
Osteoarthritis (OA) and intervertebral disc degeneration (IVDD) as major cause of chronic
low back pain represent the most common degenerative joint pathologies and are leading …
low back pain represent the most common degenerative joint pathologies and are leading …
Polymeric hydrogels for controlled drug delivery to treat arthritis
Rheumatoid arthritis (RA) and osteoarthritis (OA) are disabling musculoskeletal disorders
that affect joints and cartilage and may lead to bone degeneration. Conventional delivery of …
that affect joints and cartilage and may lead to bone degeneration. Conventional delivery of …