Crystal growth with macromolecular additives
Interactions of macromolecules with growing crystalline surfaces play an important role in
biomineralization, determine survival of some organisms at low temperatures, and offer a …
biomineralization, determine survival of some organisms at low temperatures, and offer a …
Nearly free surface silanols are the critical molecular moieties that initiate the toxicity of silica particles
Inhalation of silica particles can induce inflammatory lung reactions that lead to silicosis
and/or lung cancer when the particles are biopersistent. This toxic activity of silica dusts is …
and/or lung cancer when the particles are biopersistent. This toxic activity of silica dusts is …
Glycolipid antigens and autoantibodies in autoimmune neuropathies
HJ Willison, CS Goodyear - Trends in immunology, 2013 - cell.com
Autoantibodies to glycans present on glycolipids mediate the postinfectious paralytic
disease, Guillain–Barré syndrome (GBS). These glycans are also found on lipo …
disease, Guillain–Barré syndrome (GBS). These glycans are also found on lipo …
Hydroxyapatite nanoparticle-containing scaffolds for the study of breast cancer bone metastasis
SP Pathi, DDW Lin, JR Dorvee, LA Estroff, C Fischbach - Biomaterials, 2011 - Elsevier
Breast cancer frequently metastasizes to bone, where it leads to secondary tumor growth,
osteolytic bone degradation, and poor clinical prognosis. Hydroxyapatite Ca 10 (PO 4) 6 …
osteolytic bone degradation, and poor clinical prognosis. Hydroxyapatite Ca 10 (PO 4) 6 …
Molecular recognition between membrane epitopes and nearly free surface silanols explains silica membranolytic activity
C Pavan, MJ Sydor, C Bellomo, R Leinardi… - Colloids and Surfaces B …, 2022 - Elsevier
Inhaled crystalline silica causes inflammatory lung diseases, but the mechanism for its
unique activity compared to other oxides remains unclear, preventing the development of …
unique activity compared to other oxides remains unclear, preventing the development of …
Two polymorphic cholesterol monohydrate crystal structures form in macrophage culture models of atherosclerosis
N Varsano, F Beghi, N Elad, E Pereiro… - Proceedings of the …, 2018 - National Acad Sciences
The formation of atherosclerotic plaques in the blood vessel walls is the result of LDL
particle uptake, and consequently of cholesterol accumulation in macrophage cells. Excess …
particle uptake, and consequently of cholesterol accumulation in macrophage cells. Excess …
Crystallization of synthetic haemozoin (β-haematin) nucleated at the surface of lipid particles
AN Hoang, KK Ncokazi, KA de Villiers, DW Wright… - Dalton …, 2010 - pubs.rsc.org
The mechanism of formation of haemozoin, a detoxification by-product of several blood-
feeding organisms including malaria parasites, has been a subject of debate; however …
feeding organisms including malaria parasites, has been a subject of debate; however …
Isobutyric acid promotes colorectal cancer metastasis through activating RACK1
J Chen, J Tang, H Wang, J Mei, X Wei, X Qin… - Cancer …, 2023 - Wiley Online Library
Colorectal cancer (CRC) metastasis plays a crucial role in disease progression, yet the
regulatory mechanisms underlying metastasis remain incompletely understood. Isobutyric …
regulatory mechanisms underlying metastasis remain incompletely understood. Isobutyric …
Cholesterol microdomain enhances the biofilm eradication of antibiotic liposomes
J Xie, Z Meng, X Han, S Li, X Ma… - Advanced …, 2022 - Wiley Online Library
Resistance and tolerance of biofilms to antibiotics is the greatest challenge in the treatment
of bacterial infections. Therefore, developing an effective strategy against biofilms is a top …
of bacterial infections. Therefore, developing an effective strategy against biofilms is a top …
Spontaneous formation of two-dimensional and three-dimensional cholesterol crystals in single hydrated lipid bilayers
Grazing incidence x-ray diffraction measurements were performed on single hydrated
bilayers and monolayers of Ceramide/Cholesterol/1-palmitoyl-2-oleoyl-sn-glycero-3 …
bilayers and monolayers of Ceramide/Cholesterol/1-palmitoyl-2-oleoyl-sn-glycero-3 …