Antioxidants and atherosclerosis: mechanistic aspects

K Malekmohammad, RDE Sewell, M Rafieian-Kopaei - Biomolecules, 2019 - mdpi.com
Atherosclerosis is a chronic inflammatory disease which is a major cause of coronary heart
disease and stroke in humans. It is characterized by intimal plaques and cholesterol …

Vitamin effects on the immune system: vitamins A and D take centre stage

JR Mora, M Iwata, UH Von Andrian - Nature reviews immunology, 2008 - nature.com
Vitamins are essential constituents of our diet that have long been known to influence the
immune system. Vitamins A and D have received particular attention in recent years as …

Molecular mechanisms underlying the activation of eNOS

I Fleming - Pflügers Archiv-European Journal of Physiology, 2010 - Springer
Endothelial cells situated at the interface between blood and the vessel wall play a crucial
role in controlling vascular tone and homeostasis, particularly in determining the expression …

Oxidized LDL: diversity, patterns of recognition, and pathophysiology

I Levitan, S Volkov, PV Subbaiah - Antioxidants & redox signaling, 2010 - liebertpub.com
Oxidative modification of LDL is known to elicit an array of pro-atherogenic responses, but it
is generally underappreciated that oxidized LDL (OxLDL) exists in multiple forms …

Improving public health?: The role of antioxidant-rich fruit and vegetable beverages

PC Wootton-Beard, L Ryan - Food Research International, 2011 - Elsevier
Recent evaluations of diet quality in the UK reveal that two thirds of people still do not
consume the recommended five portions of fruit and vegetables per day. Fruit and …

Homocysteine and coronary atherosclerosis: from folate fortification to the recent clinical trials

C Antoniades, AS Antonopoulos… - European heart …, 2009 - academic.oup.com
Plasma total homocysteine (Hcy) has been associated with cardiovascular risk in multiple
large-scale epidemiological studies, and it has been considered as an independent risk …

Carvedilol and its new analogs suppress arrhythmogenic store overload–induced Ca2+ release

Q Zhou, J Xiao, D Jiang, R Wang, K Vembaiyan… - Nature medicine, 2011 - nature.com
Carvedilol is one of the most effective beta blockers for preventing ventricular
tachyarrhythmias in heart failure, but the mechanisms underlying its favorable antiarrhythmic …

The biological relevance and measurement of plasma markers of oxidative stress in diabetes and cardiovascular disease

JW Stephens, MP Khanolkar, SC Bain - Atherosclerosis, 2009 - Elsevier
Oxidative stress is associated with many chronic diseases. In this review, we look at the role
that oxidative stress may play in diabetes and related cardiovascular disease (CVD) and …

Taurine exerts hypoglycemic effect in alloxan-induced diabetic rats, improves insulin-mediated glucose transport signaling pathway in heart and ameliorates cardiac …

J Das, V Vasan, PC Sil - Toxicology and applied pharmacology, 2012 - Elsevier
Hyperlipidemia, inflammation and altered antioxidant profiles are the usual complications in
diabetes mellitus. In the present study, we investigated the therapeutic potential of taurine in …

Astaxanthin protects mitochondrial redox state and functional integrity against oxidative stress

AM Wolf, S Asoh, H Hiranuma, I Ohsawa, K Iio… - The journal of nutritional …, 2010 - Elsevier
Mitochondria combine the production of energy with an efficient chain of reduction–oxidation
(redox) reactions but also with the unavoidable production of reactive oxygen species …