[HTML][HTML] Effects of SGLT-2 inhibitors on vascular endothelial function and arterial stiffness in subjects with type 2 diabetes: a systematic review and meta-analysis of …

R Wei, W Wang, Q Pan, L Guo - Frontiers in Endocrinology, 2022 - frontiersin.org
Objective This systematic review and meta-analysis aimed to evaluate the effects of SGLT-2
inhibitors (SGLT-2i) on endothelial function and arteriosclerosis in diabetic patients …

Vascular and metabolic effects of SGLT2i and GLP-1 in heart failure patients

M Correale, O Lamacchia, M Ciccarelli, G Dattilo… - Heart Failure …, 2023 - Springer
Alterations of endothelial function, inflammatory activation, and nitric oxide-cyclic guanosine
monophosphate (NO-cGMP) pathway are involved in the pathophysiology of heart failure …

[HTML][HTML] Dapagliflozin effect on endothelial dysfunction in diabetic patients with atherosclerotic disease: a randomized active-controlled trial

AC Sposito, I Breder, AAS Soares… - Cardiovascular …, 2021 - Springer
Background The glucose-lowering independent effect of sodium glucose cotransporter-2
inhibitors (SGLT2i) on arterial wall function has not yet been clarified. This study aims to …

[HTML][HTML] Diabetic endothelial microangiopathy and pulmonary dysfunction

L Zhang, F Jiang, Y Xie, Y Mo, X Zhang… - Frontiers in …, 2023 - frontiersin.org
Type 2 diabetes mellitus (T2DM) is a widespread metabolic condition with a high global
morbidity and mortality rate that affects the whole body. Their primary consequences are …

Dapagliflozin improves endothelial cell dysfunction by regulating mitochondrial production via the SIRT1/PGC-1α pathway in obese mice

L He, Y Li, D Zhang, H Song, D Xu, Z Song - Biochemical and Biophysical …, 2022 - Elsevier
Obesity is closely related to the occurrence of cardiovascular diseases, and an important
reason for this is the induction of endothelial cell dysfunction. Mitochondria play an important …

[HTML][HTML] Effect of glycemic control on markers of subclinical atherosclerosis in patients with type 2 diabetes mellitus: A review

S Antoniou, KK Naka, M Papadakis… - World Journal of …, 2021 - ncbi.nlm.nih.gov
Cardiovascular disease is the predominant cause of death in type 2 diabetes mellitus
(T2DM). Evidence suggests a strong association between duration and degree of …

[HTML][HTML] Dapagliflozin increases the lean-to total mass ratio in type 2 diabetes mellitus

VLW Wolf, I Breder, LSF de Carvalho, AAS Soares… - Nutrition & …, 2021 - nature.com
We compared the effect of dapagliflozin versus glibenclamide on the ratio of lean-to total
mass in patients with type 2 diabetes mellitus, carotid subclinical atherosclerosis, HbA1c 7.0 …

Dapagliflozin increases retinal thickness in type 2 diabetic patients as compared with glibenclamide: a randomized controlled trial

VHR Fernandes, FRP Chaves, AAS Soares… - Diabetes & …, 2021 - Elsevier
Aim In patients with type 2 diabetes mellitus (T2DM) a progressive thinning in the central
retinal thickness (CRT) is mainly related to neuroretinal degeneration and occurs before the …

[PDF][PDF] Sodium glucose co-transporter 2 inhibitors in heart failure therapy

Y Çavuşoğlu, H Altay, A Cahn, A Çelik… - … Kardiyol Dern Ars, 2020 - jag.journalagent.com
Sodyum glikoz ko-transporter-2 inhibitörleri (SGLT-2i), glükoz geri emiliminin sağlandığı
böbrek proksimal tübüllerinde glikoz reabsorbsiyonunu engelleyip glükozuri, diürez ve …

[PDF][PDF] Effect of glycemic control on markers of subclinical atherosclerosis in patients with type 2 diabetes mellitus

S Antoniou - 2022 - olympias.lib.uoi.gr
To πολυετές ταξίδι της διατριβής φτάνει με την ολοκλήρωση της συγγραφής στο τέλος του.
Πρόκειται για έναν δύσκολο και συνάμα συναρπαστικό προσωπικό αγώνα και έργο, που …