The influence of the subcortex and brain stem on overeating: How advances in functional neuroimaging can be applied to expand neurobiological models to beyond …

PH Kung, C Soriano-Mas, T Steward - Reviews in Endocrine and …, 2022 - Springer
Functional neuroimaging has become a widely used tool in obesity and eating disorder
research to explore the alterations in neurobiology that underlie overeating and binge eating …

An open-source device for measuring food intake and operant behavior in rodent home-cages

BA Matikainen-Ankney, T Earnest, M Ali, E Casey… - Elife, 2021 - elifesciences.org
Feeding is critical for survival, and disruption in the mechanisms that govern food intake
underlies disorders such as obesity and anorexia nervosa. It is important to understand both …

Norepinephrine system at the interface of attention and reward

Y Zhang, Y Chen, Y Xin, B Peng, S Liu - Progress in Neuro …, 2023 - Elsevier
Reward learning is key to survival for individuals. Attention plays an important role in the
rapid recognition of reward cues and establishment of reward memories. Reward history …

[HTML][HTML] Anatomically and functionally distinct locus coeruleus efferents mediate opposing effects on anxiety-like behavior

O Borodovitsyna, BC Duffy, AE Pickering… - Neurobiology of …, 2020 - Elsevier
The locus coeruleus (LC) is a critical node in the stress response, and its activation has
been shown to promote hypervigilance and anxiety-like behavior. This noradrenergic …

Precise and pervasive phasic bursting in locus coeruleus during maternal behavior in mice

R Dvorkin, SD Shea - Journal of Neuroscience, 2022 - Soc Neuroscience
The noradrenergic locus coeruleus (LC) mediates key aspects of arousal, memory, and
cognition in structured tasks, but its contribution to naturalistic behavior remains unclear. LC …

[PDF][PDF] A diverse population of pericoerulear neurons controls arousal and exploratory behaviors

AT Luskin, L Li, X Fu, MM Martin, K Barcomb… - BioRxiv, 2022 - biorxiv.org
As the primary source of norepinephrine (NE) in the brain, the locus coeruleus (LC)
regulates both arousal and stress responses1, 2. However, how local neuromodulatory …

Global and subtype-specific modulation of cortical inhibitory neurons regulated by acetylcholine during motor learning

C Ren, K Peng, R Yang, W Liu, C Liu, T Komiyama - Neuron, 2022 - cell.com
Inhibitory neurons (INs) consist of distinct subtypes with unique functions. Previous studies
on INs mainly focused on single brain regions, and thus it remains unclear whether the …

Whole‐brain mapping of amylin‐induced neuronal activity in receptor activity–modifying protein 1/3 knockout mice

G Skovbjerg, U Roostalu, HH Hansen… - European Journal of …, 2021 - Wiley Online Library
The pancreatic hormone amylin plays a central role in regulating energy homeostasis and
glycaemic control by stimulating satiation and reducing food reward, making amylin receptor …

The mesencephalic trigeminal nucleus controls food intake and body weight via hindbrain POMC projections

SM Fortin, J Chen, HJ Grill, MR Hayes - Nutrients, 2021 - mdpi.com
The mesencephalic trigeminal nucleus (Mes5) processes oral sensory–motor information,
but its role in the control of energy balance remains unexplored. Here, using fluorescent in …

Sexually dimorphic role of the locus coeruleus PAC1 receptors in regulating acute stress-associated energy metabolism

SJ Duesman, S Shetty, S Patel, N Ogale… - Frontiers in Behavioral …, 2022 - frontiersin.org
Severe stress leads to alterations in energy metabolism with sexually dimorphic onset or
severity. The locus coeruleus (LC) in the brainstem that mediates fight-or-flight-or-freeze …