Neuroinflammation in Alzheimer's disease
IG Onyango, GV Jauregui, M Čarná, JP Bennett Jr… - Biomedicines, 2021 - mdpi.com
Alzheimer's disease (AD) is a neurodegenerative disease associated with human aging.
Ten percent of individuals over 65 years have AD and its prevalence continues to rise with …
Ten percent of individuals over 65 years have AD and its prevalence continues to rise with …
Mitochondrial dysfunction in microglia: A novel perspective for pathogenesis of Alzheimer's disease
Alzheimer's disease (AD) is the most common neurodegenerative disease in the elderly
globally. Emerging evidence has demonstrated microglia-driven neuroinflammation as a key …
globally. Emerging evidence has demonstrated microglia-driven neuroinflammation as a key …
Mitochondrial control of microglial phagocytosis by the translocator protein and hexokinase 2 in Alzheimer's disease
LH Fairley, KO Lai, JH Wong… - Proceedings of the …, 2023 - National Acad Sciences
Microglial phagocytosis is an energetically demanding process that plays a critical role in
the removal of toxic protein aggregates in Alzheimer's disease (AD). Recent evidence …
the removal of toxic protein aggregates in Alzheimer's disease (AD). Recent evidence …
Long-term running exercise improves cognitive function and promotes microglial glucose metabolism and morphological plasticity in the hippocampus of APP/PS1 …
S Zhang, L Zhu, Y Peng, L Zhang, F Chao… - Journal of …, 2022 - Springer
Background The role of physical exercise in the prevention of Alzheimer's disease (AD) has
been widely studied. Microglia play an important role in AD. Triggering receptor expressed …
been widely studied. Microglia play an important role in AD. Triggering receptor expressed …
The role of glial autophagy in Alzheimer's disease
A Litwiniuk, GR Juszczak, AM Stankiewicz… - Molecular …, 2023 - nature.com
Although Alzheimer's disease is the most pervasive neurodegenerative disorder, the
mechanism underlying its development is still not precisely understood. Available data …
mechanism underlying its development is still not precisely understood. Available data …
Alzheimer's disease and inflammaging
AM Kosyreva, AV Sentyabreva, IS Tsvetkov… - Brain sciences, 2022 - mdpi.com
Alzheimer's disease is one of the most common age-related neurodegenerative disorders.
The main theory of Alzheimer's disease progress is the amyloid-β cascade hypothesis …
The main theory of Alzheimer's disease progress is the amyloid-β cascade hypothesis …
The role of the immune system in Alzheimer's disease
KM Wu, YR Zhang, YY Huang, Q Dong, L Tan… - Ageing research …, 2021 - Elsevier
Alzheimer's disease (AD) is the most common neurodegenerative disorder where the
accumulation of amyloid plaques and the formation of tau tangles are the prominent …
accumulation of amyloid plaques and the formation of tau tangles are the prominent …
Integrated multi-omics analysis of Alzheimer's disease shows molecular signatures associated with disease progression and potential therapeutic targets
P Kodam, R Sai Swaroop, SS Pradhan… - Scientific reports, 2023 - nature.com
Alzheimer's disease (AD) is a progressive neurodegenerative disease characterized by the
formation of amyloid plaques implicated in neuronal death. Genetics, age, and sex are the …
formation of amyloid plaques implicated in neuronal death. Genetics, age, and sex are the …
Mitochondria transfer in brain injury and disease
Intercellular mitochondria transfer is a novel form of cell signalling in which whole
mitochondria are transferred between cells in order to enhance cellular functions or aid in …
mitochondria are transferred between cells in order to enhance cellular functions or aid in …
Near-infrared light reduces β-amyloid-stimulated microglial toxicity and enhances survival of neurons: Mechanisms of light therapy for Alzheimer's disease
YV Stepanov, I Golovynska, R Zhang… - Alzheimer's research & …, 2022 - Springer
Background Low-intensity light can decelerate neurodegenerative disease progression and
reduce amyloid β (Aβ) levels in the cortex, though the cellular and molecular mechanisms by …
reduce amyloid β (Aβ) levels in the cortex, though the cellular and molecular mechanisms by …