Neuroinflammatory markers: key indicators in the pathology of neurodegenerative diseases
Neuroinflammation, a protective response of the central nervous system (CNS), is
associated with the pathogenesis of neurodegenerative diseases. The CNS is composed of …
associated with the pathogenesis of neurodegenerative diseases. The CNS is composed of …
The gap junction communication channel
NM Kumar, NB Gilula - Cell, 1996 - cell.com
Communication plays an important role in the rapid Connexin Structure progress of modern
society. We live in an age when Gap junctions exhibit a hierarchy of assembly. The …
society. We live in an age when Gap junctions exhibit a hierarchy of assembly. The …
Plasma membrane channels formed by connexins: their regulation and functions
JC Sáez, VM Berthoud, MC Branes… - Physiological …, 2003 - journals.physiology.org
Sáez, Juan C., Viviana M. Berthoud, María C. Brañes, Agustín D. Martínez, and Eric C.
Beyer. Plasma Membrane Channels Formed by Connexins: Their Regulation and Functions …
Beyer. Plasma Membrane Channels Formed by Connexins: Their Regulation and Functions …
Beyond the one gene–one disease paradigm: complex genetics and pleiotropy in inheritable cardiac disorders
Inheritable cardiac disorders, which may be associated with cardiomyopathic changes, are
often associated with increased risk of sudden death in the young. Early linkage analysis …
often associated with increased risk of sudden death in the young. Early linkage analysis …
Life cycle of connexins in health and disease
DW Laird - Biochemical Journal, 2006 - portlandpress.com
Evaluation of the human genome suggests that all members of the connexin family of gap-
junction proteins have now been successfully identified. This large and diverse family of …
junction proteins have now been successfully identified. This large and diverse family of …
Endocrine and paracrine regulation of birth at term and preterm
We have examined factors concerned with the maintenance of uterine quiescence during
pregnancy and the onset of uterine activity at term in an animal model, the sheep, and in …
pregnancy and the onset of uterine activity at term in an animal model, the sheep, and in …
Gap junction protein Connexin-43 is a direct transcriptional regulator of N-cadherin in vivo
Connexins are the primary components of gap junctions, providing direct links between cells
under many physiological processes. Here, we demonstrate that in addition to this canonical …
under many physiological processes. Here, we demonstrate that in addition to this canonical …
Connections with connexins: the molecular basis of direct intercellular signaling
R Bruzzone, TW White, DL Paul - European journal of …, 1996 - Wiley Online Library
Adjacent cells share ions, second messengers and small metabotes through intercellular
channels which are present in gap junctions. This type of intercellular communication …
channels which are present in gap junctions. This type of intercellular communication …
Intercellular Ca2+ Waves: Mechanisms and Function
L Leybaert, MJ Sanderson - Physiological reviews, 2012 - journals.physiology.org
Intercellular calcium (Ca2+) waves (ICWs) represent the propagation of increases in
intracellular Ca2+ through a syncytium of cells and appear to be a fundamental mechanism …
intracellular Ca2+ through a syncytium of cells and appear to be a fundamental mechanism …
Beyond the gap: functions of unpaired connexon channels
DA Goodenough, DL Paul - Nature reviews Molecular cell biology, 2003 - nature.com
Gap junctions consist of intercellular channels that connect the cytoplasm of adjacent cells
directly and allow the exchange of small molecules. These channels are unique in that they …
directly and allow the exchange of small molecules. These channels are unique in that they …