Physiology and evolution of voltage-gated calcium channels in early diverging animal phyla: Cnidaria, Placozoa, Porifera and Ctenophora
A Senatore, H Raiss, P Le - Frontiers in physiology, 2016 - frontiersin.org
Voltage-gated calcium (Cav) channels serve dual roles in the cell, where they can both
depolarize the membrane potential for electrical excitability, and activate transient …
depolarize the membrane potential for electrical excitability, and activate transient …
Selectivity filters and cysteine-rich extracellular loops in voltage-gated sodium, calcium, and NALCN channels
RF Stephens, W Guan, BS Zhorov… - Frontiers in …, 2015 - frontiersin.org
How nature discriminates sodium from calcium ions in eukaryotic channels has been difficult
to resolve because they contain four homologous, but markedly different repeat domains …
to resolve because they contain four homologous, but markedly different repeat domains …
Toxicity of antimony to Daphnia magna: influence of environmental factors, development of biotic ligand approach and biochemical response at environmental …
Y Li, H Li, R Zhang, X Bing - Journal of Hazardous Materials, 2024 - Elsevier
Acute toxicity of antimony pentavalent to neonatal Daphnia magna and the influence of
water quality parameters were investigated, and enzymatic activities of organisms at …
water quality parameters were investigated, and enzymatic activities of organisms at …
CaV1.3 L-type Ca2+ channel contributes to the heartbeat by generating a dihydropyridine-sensitive persistent Na+ current
F Toyoda, P Mesirca, S Dubel, WG Ding, J Striessnig… - Scientific Reports, 2017 - nature.com
The spontaneous activity of sinoatrial node (SAN) pacemaker cells is generated by a
functional interplay between the activity of ionic currents of the plasma membrane and …
functional interplay between the activity of ionic currents of the plasma membrane and …
Eukaryotic voltage-gated sodium channels: on their origins, asymmetries, losses, diversification and adaptations
JE Fux, A Mehta, J Moffat, JD Spafford - Frontiers in Physiology, 2018 - frontiersin.org
The appearance of voltage-gated, sodium-selective channels with rapid gating kinetics was
a limiting factor in the evolution of nervous systems. Two rounds of domain duplications …
a limiting factor in the evolution of nervous systems. Two rounds of domain duplications …
Evolutionary insights into T-type Ca2+ channel structure, function, and ion selectivity from the Trichoplax adhaerens homologue
Four-domain voltage-gated Ca2+ (Cav) channels play fundamental roles in the nervous
system, but little is known about when or how their unique properties and cellular roles …
system, but little is known about when or how their unique properties and cellular roles …
Diversity and evolution of four-domain voltage-gated cation channels of eukaryotes and their ancestral functional determinants
I Pozdnyakov, O Matantseva, S Skarlato - Scientific reports, 2018 - nature.com
Four-domain voltage-gated cation channels (FVCCs) represent a large family of pseudo-
tetrameric ion channels which includes voltage-gated calcium (Cav) and sodium (Nav) …
tetrameric ion channels which includes voltage-gated calcium (Cav) and sodium (Nav) …
Deciphering the underlying mechanisms of the pharyngeal pumping motions in Caenorhabditis elegans
D Sherman, D Harel - … of the National Academy of Sciences, 2024 - National Acad Sciences
The pharynx of the nematode Caenorhabditis elegans is a neuromuscular organ that
exhibits typical pumping motions, which result in the intake of food particles from the …
exhibits typical pumping motions, which result in the intake of food particles from the …
Divergent Ca2+/calmodulin feedback regulation of CaV1 and CaV2 voltage-gated calcium channels evolved in the common ancestor of Placozoa and Bilateria
Ca V 1 and Ca V 2 voltage-gated calcium channels evolved from an ancestral Ca V 1/2
channel via gene duplication somewhere near the stem animal lineage. The divergence of …
channel via gene duplication somewhere near the stem animal lineage. The divergence of …
Acute dysprosium toxicity to Daphnia pulex and Hyalella azteca and development of the biotic ligand approach
The toxicological understanding of rare earth elements (REEs) in the aquatic environment is
very limited but of increasing concern. The objective of this research is to compare the …
very limited but of increasing concern. The objective of this research is to compare the …