Activity modeling, molecular docking and pharmacokinetic studies of some boron-pleuromutilins as anti-wolbachia agents with potential for treatment of filarial …

FA Ugbe, GA Shallangwa, A Uzairu… - Chemical Data Collections, 2021 - Elsevier
Lymphatic filariasis and Onchocerciasis remain one of the oldest known Neglected Tropical
Diseases (NTD) caused by a group of parasitic filarial nematodes co-habiting with the …

Traditional Methods for Treatment and Management of Measles in Northern Nigeria: Medicinal plants and their molecular docking

MD Abdulrahman, SW Hamad - Ethnobotany Research and …, 2022 - eprints.tiu.edu.iq
Background: Measles is one of the major causes of death among young children worldwide.
According to the World Health Organization, measles affects more than 20 million people …

Theoretical activity prediction, structure-based design, molecular docking and pharmacokinetic studies of some maleimides against Leishmania donovani for the …

FA Ugbe, GA Shallangwa, A Uzairu… - Bulletin of the National …, 2022 - Springer
Background Leishmaniasis is a neglected tropical disease caused by a group of protozoan
of the genus Leishmani a and transmitted to humans majorly through the bite of the female …

A combined 2-D and 3-D QSAR modeling, molecular docking study, design, and pharmacokinetic profiling of some arylimidamide-azole hybrids as superior L …

FA Ugbe, GA Shallangwa, A Uzairu… - Bulletin of the National …, 2022 - Springer
Background Leishmaniasis is one of the neglected tropical diseases which is prevalent in
the tropical regions of the world most especially in Africa. It is caused by the Leishmania …

Theoretical modeling and design of some pyrazolopyrimidine derivatives as Wolbachia inhibitors, targeting lymphatic filariasis and onchocerciasis

FA Ugbe, GA Shallangwa, A Uzairu, I Abdulkadir - In Silico Pharmacology, 2022 - Springer
Lymphatic filariasis and onchocerciasis are two common filarial diseases caused by a group
of parasitic nematodes called filarial worms, which play host to the bacteria organism …

[PDF][PDF] Combined QSAR modeling, molecular docking screening, and pharmacokinetics analyses for the design of novel 2, 6-diarylidene cyclohexanone analogs as …

FA Ugbe, GA Shallangwa… - Progress in Chemical …, 2023 - researchgate.net
Leishmaniasis, a neglected tropical disease is known to infect over 12 million people mainly
in tropical Africa, Southeast Asia, and Latin America [1]. Visceral leishmaniasis (VL) is the …

Molecular docking-based virtual screening, molecular dynamic simulation, and 3-D QSAR modeling of some pyrazolopyrimidine analogs as potent anti-filarial agents

FA Ugbe, GA Shallangwa, A Uzairu, I Abdulkadir - In Silico Pharmacology, 2022 - Springer
Lymphatic filariasis and onchocerciasis are common filarial diseases caused by filarial
worms, which co-habit symbiotically with the Wolbachia organism. One good treatment …

[HTML][HTML] Ligand based-design of potential schistosomiasis inhibitors through QSAR, homology modeling, molecular dynamics, pharmacokinetics, and DFT studies

C Saudatu, A Uzairu, A Chandra, MS Sallau… - Journal of Taibah …, 2024 - Elsevier
Schistosomiasis, also known as bilharzia or snail fever, is a tropical disease caused by
parasitic flatworms belonging to the Schistosoma genus. This disease remains a prevalent …

[HTML][HTML] 2D-QSAR, molecular docking, drug-likeness, and ADMET/pharmacokinetic predictions of some non-small cell lung cancer therapeutic agents

MT Ibrahim, A Uzairu - Journal of Taibah University Medical Sciences, 2023 - Elsevier
Stanley Cohen discovered epidermal growth factor receptor (EGFR) in 1956 while working
at Vanderbilt University (Nashville, TN, USA). 1 EGFR is a member of the ErbB family of …

Molecular docking investigation and pharmacokinetic properties prediction of some anilinopyrimidines analogues as egfr t790m tyrosine kinase inhibitors

MT Ibrahim, A Uzairu, GA Shallangwa… - Egyptian journal of basic …, 2021 - Taylor & Francis
The most common and deadly type of lung cancers around the globe was the non-small-cell
lung cancer with approximately 1.5 million cases and a 5-year survival rate of less than 20 …