Identifying frail patients by using electronic health records in primary care: current status and future directions

J Luo, X Liao, C Zou, Q Zhao, Y Yao, X Fang… - Frontiers in Public …, 2022 - frontiersin.org
With the rapidly aging population, frailty, characterized by an increased risk of adverse
outcomes, has become a major public health problem globally. Several frailty guidelines or …

[HTML][HTML] How I treat multiple myeloma in geriatric patients

T Facon, X Leleu, S Manier - Blood, 2024 - Elsevier
Multiple myeloma (MM) is primarily a disease of elderly patients. Geriatric aspects in the
context of MM have been poorly investigated until recently. Treatment outcomes for geriatric …

Dynamic frailty risk assessment among older adults with multiple myeloma: A population-based cohort study

H Mian, TM Wildes, R Vij, MJ Pianko, A Major… - Blood cancer …, 2023 - nature.com
Multiple myeloma (MM) is a cancer of older adults and those who are more frail are at high
risk of poor outcomes. Current tools for identifying and categorizing frail patients are often …

More intensive therapy has a better effect for frail parents with multiple myeloma

C DuMontier, J La, J Bihn, J Corrigan… - Blood …, 2023 - ashpublications.org
Although randomized controlled trial data suggest that the more intensive triplet bortezomib-
lenalidomide-dexamethasone (VRd) is superior to the less intensive doublet lenalidomide …

Assessment of an embedded primary care-derived electronic health record (EHR) frailty index (eFI) in older adults with acute myeloid leukemia

JJ Cheng, JA Tooze, KE Callahan, NM Pajewski… - Journal of geriatric …, 2023 - Elsevier
Introduction Assessing frailty is integral to treatment decision-making for older adults with
acute myeloid leukemia (AML). Prior electronic frailty indices (eFI) derive from an …

Frailty and survival among veterans treated with abiraterone or enzalutamide for metastatic castration-resistant prostate cancer

ES Deol, KM Sanfilippo, S Luo, MA Fiala… - Journal of Geriatric …, 2023 - Elsevier
Introduction Abiraterone and enzalutamide are treatments for metastatic castration-resistant
prostate cancer (mCRPC). Due to a lack of head-to-head trials, they are prescribed …

Frailty assessment using routine clinical data: an integrative review

A Lim, JY Choi, H Ji, H Lee - Archives of Gerontology and Geriatrics, 2022 - Elsevier
Background: Frailty is a common but complex problem in older adults. Frailty assessment
using routine clinical data has been suggested as a pragmatic approach based on …

Construct validity of the electronic Veterans Affairs Frailty Index against clinician frailty assessment

C DuMontier, R Hennis, C Yilidirim… - Journal of the …, 2023 - Wiley Online Library
Background Electronic frailty indices (eFIs) can expand measurement of frailty in research
and practice and have demonstrated predictive validity in associations with clinical …

Natural Language Processing–Assisted Classification Models to Confirm Monoclonal Gammopathy of Undetermined Significance and Progression in Veterans' …

M Wang, YC Yu, L Liu, MW Schoen, A Kumar… - JCO Clinical Cancer …, 2023 - ascopubs.org
PURPOSE To develop and validate natural language processing (NLP)–assisted machine
learning (ML)–based classification models to confirm diagnoses of monoclonal gammopathy …

Validation of algorithms to select patients with multiple myeloma and patients initiating myeloma treatment in the national Veterans Affairs Healthcare System

J La, C DuMontier, H Hassan… - … and drug safety, 2023 - Wiley Online Library
Background We aimed to evaluate and compare the performance of multiple myeloma (MM)
selection algorithms for use in Veterans Affairs (VA) research. Methods Using the VA …