Intracellular organelles are subsystems within a cell, whose activity and chemical
composition reflect the metabolic state of live cells. Alterations in cellular homeostasis …

Over the past decade, we have seen rapid advances in applying nanotechnology in
biomedical areas including bioimaging, biodetection, and drug delivery. As an emerging …

Exploring and understanding biological and pathological changes are of great significance
for early diagnosis and therapy of diseases. Optical sensing and imaging approaches have …

Beyond traditional needs of biosensors such as high sensitivity and selectivity for analyte
detection, newly emerging requirements including a real-time detection ability and in-field …

Development of biosensing platforms plays a key role in research settings for identification
of biomarkers and in clinical applications for diagnostics. Biosensors based on nucleic acids …

Researchers have worked for many decades to master the rules of biomolecular design that
would allow artificial biopolymer complexes to self-assemble and function similarly to the …

Designer DNA nanodevices have attracted extensive interest for detection of specific targets
in living cells. However, it still remains a great challenge to construct DNA sensing devices …

DNA origami has played an important role in various biomedical applications, including
biosensing, bioimaging, and drug delivery. However, the function of the long DNA scaffold …

DNA-based probes constitute a versatile platform for making biological measurements due
to their ability to recognize both nucleic acid and non-nucleic acid targets, ease of synthesis …

Advances in bioimaging technologies have led to unprecedented findings of novel
biological processes at the nanoscale. However, there remains an ever-lasting demand for …