Transposable elements (TEs) comprise about half of the mammalian genome. TEs often
contain sequences capable of recruiting the host transcription machinery, which they use to …

In the past two decades, record-breaking heatwaves have caused an increasing number of
heat-related deaths, including heatstroke, globally. Heatstroke is a heat illness characterized …

Blood analyses provide substantial information about the physiological aspects of animal
welfare assessment, including the activation status of the neuroendocrine and immune …

INTRODUCTION In response to many types of stress, eukaryotic cells initiate an adaptive
and reversible response that includes down-regulation of key cellular activities along with …

Flexible manipulation of the fate of cancer cells through exogenous stimulation-induced
metabolic reprogramming could handle the cellular plasticity-derived therapies resistance …

The programmes that direct an organism's development and maintenance are encoded in its
genome. Decoding of this information begins with regulated transcription of genomic DNA …

Transcription is orchestrated by thousands of transcription factors (TFs) and chromatin-
associated proteins, but how these are causally connected to transcriptional activation is …

To thrive and to fulfill their functions, cells need to maintain proteome homeostasis even in
the face of adverse environmental conditions or radical restructuring of the proteome during …

All cells possess an internal stress response to cope with environmental and
pathophysiological challenges. Upon stress, cells reprogram their molecular functions to …

Cellular homeostasis requires transcriptional outputs to be coordinated, and many events
post-transcription initiation can dictate the levels and functions of mature transcripts. To …