Early developmental conditioning of later health and disease: physiology or pathophysiology?

MA Hanson, PD Gluckman - Physiological reviews, 2014 - journals.physiology.org
Extensive experimental animal studies and epidemiological observations have shown that
environmental influences during early development affect the risk of later pathophysiological …

Fatty acids, epigenetic mechanisms and chronic diseases: a systematic review

K González-Becerra, O Ramos-López… - Lipids in health and …, 2019 - Springer
Background Chronic illnesses like obesity, type 2 diabetes (T2D) and cardiovascular
diseases, are worldwide major causes of morbidity and mortality. These pathological …

Maternal obesity and fetal metabolic programming: a fertile epigenetic soil

MJR Heerwagen, MR Miller… - American Journal of …, 2010 - journals.physiology.org
The incidence of obesity and overweight has reached epidemic levels in the United States
and developed countries worldwide. Even more alarming is the increasing prevalence of …

Developmental origins of metabolic disease: life course and intergenerational perspectives

KM Godfrey, PD Gluckman, MA Hanson - Trends in Endocrinology & …, 2010 - cell.com
Recent evidence demonstrates important maternal effects on an offspring's risk of
developing metabolic disease. These effects extend across the full range of maternal …

Impact of Maternal Diet on the Epigenome during In Utero Life and the Developmental Programming of Diseases in Childhood and Adulthood

HS Lee - Nutrients, 2015 - mdpi.com
Exposure to environmental factors in early life can influence developmental processes and
long-term health in humans. Early life nutrition and maternal diet are well-known examples …

Developmental programming in response to maternal overnutrition

MZ Alfaradhi, SE Ozanne - Frontiers in genetics, 2011 - frontiersin.org
Metabolic disorders have seen an increased prevalence in recent years in developed as
well as developing countries. While it is clear lifestyle choices and habits have contributed to …

Obesity in pregnancy: implications for the mother and lifelong health of the child. A consensus statement

L Poston, LF Harthoorn, EM Van Der Beek - Pediatric research, 2011 - nature.com
Obesity among pregnant women is becoming one of the most important women's health
issues. Obesity is associated with increased risk of almost all pregnancy complications …

The role of nutrition on epigenetic modifications and their implications on health

JC Jiménez-Chillarón, R Díaz, D Martínez, T Pentinat… - Biochimie, 2012 - Elsevier
Nutrition plays a key role in many aspects of health and dietary imbalances are major
determinants of chronic diseases including cardiovascular disease, obesity, diabetes and …

Early nutrition programming of long-term health

B Koletzko, B Brands, L Poston, K Godfrey… - Proceedings of the …, 2012 - cambridge.org
Increasing evidence from the EU Project EARNEST and many other investigators
demonstrates that early nutrition and lifestyle have long-term effects on later health and the …

Developmental plasticity and developmental origins of non-communicable disease: theoretical considerations and epigenetic mechanisms

M Hanson, KM Godfrey, KA Lillycrop, GC Burdge… - Progress in biophysics …, 2011 - Elsevier
There is now evidence that developmental influences have lifelong effects on cardiovascular
and metabolic function and that elements of the heritable or familial component of …