Preeclampsia is a major cause of maternal and perinatal morbidity and mortality. Early-onset
disease requiring preterm delivery is associated with a higher risk of complications in both …

The established method of the assessment of the risk for development of preeclampsia is to
identify risk factors from maternal demographic characteristics and medical history; in the …

Preeclampsia (PE) is a multisystem disorder that typically affects 2%− 5% of pregnant
women and is one of the leading causes of maternal and perinatal morbidity and mortality …

Background Preeclampsia affects approximately 3% of all pregnancies and is a major cause
of maternal and perinatal morbidity and death. In the last decade, extensive research has …

Metformin is everywhere. Originally introduced in clinical practice as an antidiabetic agent,
its role as a therapeutic agent is expanding to include treatment of prediabetes mellitus …

Preeclampsia is a potentially serious complication of pregnancy with increasing significance
worldwide. Preeclampsia is the cause of 9%–26% of global maternal mortality and a …

Effective screening for the development of early onset preeclampsia (PE) can be provided in
the first‐trimester of pregnancy. Screening by a combination of maternal risk factors, uterine …

The placenta is a transient organ that forms during pregnancy to support the growth and
development of the fetus. During human placental development, trophoblast cells …

This study aimed to establish a method of screening for pregnancy hypertension by a
combination of maternal variables, including mean arterial pressure, uterine artery pulsatility …

Please cite this paper as: Kleinrouweler C, Wiegerinck M, Ris‐Stalpers C, Bossuyt P, van
der Post J, von Dadelszen P, Mol B, Pajkrt E, for the EBM CONNECT Collaboration …