Role of pyroptosis in inflammation and cancer
X Wei, F Xie, X Zhou, Y Wu, H Yan, T Liu… - Cellular & molecular …, 2022 - nature.com
Pyroptosis is a form of programmed cell death mediated by gasdermin and is a product of
continuous cell expansion until the cytomembrane ruptures, resulting in the release of …
continuous cell expansion until the cytomembrane ruptures, resulting in the release of …
RNA-binding proteins in cancer: old players and new actors
RNA-binding proteins (RBPs) are key players in post-transcriptional events. The
combination of versatility of their RNA-binding domains with structural flexibility enables …
combination of versatility of their RNA-binding domains with structural flexibility enables …
A macrophage-specific lncRNA regulates apoptosis and atherosclerosis by tethering HuR in the nucleus
Long non-coding RNAs (lncRNAs) are emerging regulators of pathophysiological processes
including atherosclerosis. Using RNA-seq profiling of the intima of lesions, here we identify a …
including atherosclerosis. Using RNA-seq profiling of the intima of lesions, here we identify a …
[HTML][HTML] Anti-apoptosis and cell survival: a review
L Portt, G Norman, C Clapp, M Greenwood… - … et Biophysica Acta (BBA …, 2011 - Elsevier
Type I programmed cell death (PCD) or apoptosis is critical for cellular self-destruction for a
variety of processes such as development or the prevention of oncogenic transformation …
variety of processes such as development or the prevention of oncogenic transformation …
RNA-binding proteins in cancer: functional and therapeutic perspectives
D Kang, Y Lee, JS Lee - Cancers, 2020 - mdpi.com
Simple Summary RNA-binding proteins (RBPs) play central roles in regulating
posttranscriptional expression of genes. Many of them are known to be deregulated in a …
posttranscriptional expression of genes. Many of them are known to be deregulated in a …
[HTML][HTML] HuR function in disease
S Srikantan, M Gorospe - Frontiers in bioscience (Landmark edition …, 2012 - ncbi.nlm.nih.gov
The cytoplasmic events that control mammalian gene expression, primarily mRNA stability
and translation, potently influence the cellular response to internal and external signals. The …
and translation, potently influence the cellular response to internal and external signals. The …
Diverse molecular functions of Hu proteins
MN Hinman, H Lou - Cellular and molecular life sciences, 2008 - Springer
Hu proteins are RNA-binding proteins involved in diverse biological processes. The
neuronal members of the Hu family, HuB, HuC, and HuD play important roles in neuronal …
neuronal members of the Hu family, HuB, HuC, and HuD play important roles in neuronal …
Posttranscriptional regulation of cancer traits by HuR
K Abdelmohsen, M Gorospe - Wiley Interdisciplinary Reviews …, 2010 - Wiley Online Library
Cancer‐related gene expression programs are strongly influenced by posttranscriptional
mechanisms. The RNA‐binding protein HuR is highly abundant in many cancers. Numerous …
mechanisms. The RNA‐binding protein HuR is highly abundant in many cancers. Numerous …
[HTML][HTML] RNA binding proteins (RBPs) and their role in DNA damage and radiation response in cancer
Traditionally majority of eukaryotic gene expression is influenced by transcriptional and post-
transcriptional events. Alterations in the expression of proteins that act post-transcriptionally …
transcriptional events. Alterations in the expression of proteins that act post-transcriptionally …
RNA-binding protein nucleolin in disease
K Abdelmohsen, M Gorospe - RNA biology, 2012 - Taylor & Francis
Nucleolin is a multifunctional protein localized primarily in the nucleolus, but also found in
the nucleoplasm, cytoplasm and cell membrane. It is involved in several aspects of DNA …
the nucleoplasm, cytoplasm and cell membrane. It is involved in several aspects of DNA …