ROS signaling cascades: dual regulations for osteoclast and osteoblast
H Tao, G Ge, X Liang, W Zhang, H Sun… - Acta Biochimica et …, 2020 - academic.oup.com
Accumulating evidence indicates that intracellular reactive oxygen species (ROS)
production is highly involved in bone homeostasis by intervening osteoclast or osteoblast …
production is highly involved in bone homeostasis by intervening osteoclast or osteoblast …
Influence of iron on bone homeostasis
Bone homeostasis is a complex process, wherein osteoclasts resorb bone and osteoblasts
produce new bone tissue. For the maintenance of skeletal integrity, this sequence has to be …
produce new bone tissue. For the maintenance of skeletal integrity, this sequence has to be …
Regulating Type H Vessel Formation and Bone Metabolism via Bone‐Targeting Oral Micro/Nano‐Hydrogel Microspheres to Prevent Bone Loss
Postmenopausal osteoporosis is one of the most prevalent skeletal disorders in women and
is featured by the imbalance between intraosseous vascularization and bone metabolism. In …
is featured by the imbalance between intraosseous vascularization and bone metabolism. In …
Long Bone Mineral Loss, Bone Microstructural Changes and Oxidative Stress After Eimeria Challenge in Broilers
The objective of this study was to evaluate the impact of coccidiosis on bone quality and
antioxidant status in the liver and bone marrow of broiler chickens. A total of 360 13-day old …
antioxidant status in the liver and bone marrow of broiler chickens. A total of 360 13-day old …
HO-1 in bone biology: potential therapeutic strategies for osteoporosis
X Zhou, W Yuan, X Xiong, Z Zhang, J Liu… - Frontiers in Cell and …, 2021 - frontiersin.org
Osteoporosis is a prevalent bone disorder characterized by bone mass reduction and
deterioration of bone microarchitecture leading to bone fragility and fracture risk. In recent …
deterioration of bone microarchitecture leading to bone fragility and fracture risk. In recent …
Ginsenoside compound-K attenuates OVX-induced osteoporosis via the suppression of RANKL-induced osteoclastogenesis and oxidative stress
L Ding, Z Gao, S Wu, C Chen, Y Liu, M Wang… - Natural Products and …, 2023 - Springer
Osteoporosis (OP), a systemic and chronic bone disease, is distinguished by low bone mass
and destruction of bone microarchitecture. Ginsenoside Compound-K (CK), one of the …
and destruction of bone microarchitecture. Ginsenoside Compound-K (CK), one of the …
Targeting Sirt1, AMPK, Nrf2, CK2, and soluble guanylate cyclase with nutraceuticals: a practical strategy for preserving bone mass
MF McCarty, L Lewis Lujan, S Iloki Assanga - International Journal of …, 2022 - mdpi.com
There is a vast pre-clinical literature suggesting that certain nutraceuticals have the potential
to aid the preservation of bone mass in the context of estrogen withdrawal, glucocorticoid …
to aid the preservation of bone mass in the context of estrogen withdrawal, glucocorticoid …
MicroRNAs: key regulators to understand osteoclast differentiation?
C Lozano, I Duroux-Richard, H Firat… - Frontiers in …, 2019 - frontiersin.org
MicroRNAs (miRNAs) are small non-coding single-stranded RNAs that represent important
posttranscriptional regulators of protein-encoding genes. In particular, miRNAs play key …
posttranscriptional regulators of protein-encoding genes. In particular, miRNAs play key …
Absence of dipeptidyl peptidase 3 increases oxidative stress and causes bone loss
Controlling oxidative stress through the activation of antioxidant pathways is crucial in bone
homeostasis, and impairments of the cellular defense systems involved contribute to the …
homeostasis, and impairments of the cellular defense systems involved contribute to the …
CYT387, a JAK-Specific Inhibitor Impedes Osteoclast Activity and Oophorectomy-Induced Osteoporosis via Modulating RANKL and ROS Signaling Pathways
J Li, J Liang, L Wu, Y Xu, C Xiao, X Yang… - Frontiers in …, 2022 - frontiersin.org
Osteoclasts are of hematopoietic lineage and have the ability to degrade mineralized bone
tissues. Abnormalities in osteoclastic activity under certain pathological conditions are …
tissues. Abnormalities in osteoclastic activity under certain pathological conditions are …