Chronic beryllium disease (CBD) is a lung disorder related to beryllium exposure and is
characterized by the accumulation in the lung of beryllium-specific CD4+ major …

Susceptibility to murine and human insulin-dependent diabetes mellitus correlates strongly
with major histocompatibility complex (MHC) class II IA or HLA-DQ alleles that lack an …

A novel mechanism for inhibition of T cell responses is described. Using the recognition of
the influenza hemagglutinin(HA) 307-319 peptide in the context of DFll class II major …

The synthetic random amino acid copolymer Copolymer 1 (Cop 1, Copaxone, glatiramer
acetate) suppresses experimental autoimmune encephalomyelitis, slows the progression of …

Susceptibility to insulin-dependent diabetes mellitus is linked to MHC class II genes. The
only MHC class II molecule expressed by nonobese diabetic (NOD) mice, IA g7, shares a …

Family and population studies indicate that several different genes can increase
susceptibility to autoimmune diseases. Established genetic risk factors include genes …

The class II major histocompatibility complex molecule I-Ag7 is strongly linked to the
development of spontaneous insulin-dependent diabetes mellitus (IDDM) in non obese …

In the present study, we examined the therapeutic effects of T-614 (3-formylamino-7-
methylsulfonylamino-6-phenoxy-4H-1-benzopyran-4-one), a new anti-rheumatic drug, on a …

Heymann nephritis is an experimental autoimmune disease model for human membranous
nephropathy. We have recently identified a pathogenic epitope, clone 14 (C14), responsible …

The past decade has seen great advances in our understanding of the pathogenesis of
IDDM. This knowledge has led to investigative use of a battery of immunologic, genetic, and …