CAR T therapies in multiple myeloma: Unleashing the future
M Sheykhhasan, A Ahmadieh-Yazdi… - Cancer Gene …, 2024 - nature.com
In recent years, the field of cancer treatment has witnessed remarkable breakthroughs that
have revolutionized the landscape of care for cancer patients. While traditional pillars such …
have revolutionized the landscape of care for cancer patients. While traditional pillars such …
Chimeric antigen receptor-modified T cell therapy in multiple myeloma: beyond B cell maturation antigen
M Timmers, G Roex, Y Wang… - Frontiers in …, 2019 - frontiersin.org
Chimeric antigen receptor (CAR)-modified T cell therapy is a rapidly emerging
immunotherapeutic approach that is revolutionizing cancer treatment. The impressive …
immunotherapeutic approach that is revolutionizing cancer treatment. The impressive …
Targeting TGF-β signaling in the multiple myeloma microenvironment: Steering CARs and T cells in the right direction
Multiple myeloma (MM) remains a lethal hematologic cancer characterized by the expansion
of transformed plasma cells within the permissive bone marrow (BM) milieu. The emergence …
of transformed plasma cells within the permissive bone marrow (BM) milieu. The emergence …
Incidence and clinical features of extramedullary multiple myeloma in patients who underwent stem cell transplantation
M Weinstock, Y Aljawai, EA Morgan… - British journal of …, 2015 - Wiley Online Library
Extramedullary disease (EMD), defined as an infiltrate of clonal plasma cells at an anatomic
site distant from the bone marrow, is an uncommon manifestation of multiple myeloma. Six …
site distant from the bone marrow, is an uncommon manifestation of multiple myeloma. Six …
The oncogenic transcription factor IRF4 is regulated by a novel CD30/NF-κB positive feedback loop in peripheral T-cell lymphoma
RL Boddicker, NS Kip, X Xing, Y Zeng… - Blood, The Journal …, 2015 - ashpublications.org
Peripheral T-cell lymphomas (PTCLs) are generally aggressive non-Hodgkin lymphomas
with poor overall survival rates following standard therapy. One-third of PTCLs express …
with poor overall survival rates following standard therapy. One-third of PTCLs express …
Any closer to successful therapy of multiple myeloma? CAR-T cell is a good reason for optimism
F Marofi, S Tahmasebi, HS Rahman… - Stem cell research & …, 2021 - Springer
Despite many recent advances on cancer novel therapies, researchers have yet a long way
to cure cancer. They have to deal with tough challenges before they can reach success …
to cure cancer. They have to deal with tough challenges before they can reach success …
Multiple myeloma: New surface antigens for the characterization of plasma cells in the era of novel agents
VE Muccio, E Saraci, M Gilestro, V Gattei… - Cytometry Part B …, 2016 - Wiley Online Library
ABSTRACT Background Multiple Myeloma (MM) is a neoplastic disorder characterized by
clonal proliferation of malignant plasma cells (PCs). Flow cytometry is an essential tool to …
clonal proliferation of malignant plasma cells (PCs). Flow cytometry is an essential tool to …
Mass Cytometry reveals unique phenotypic patterns associated with subclonal diversity and outcomes in multiple myeloma
Multiple myeloma (MM) remains an incurable plasma cell (PC) malignancy. Although it is
known that MM tumor cells display extensive intratumoral genetic heterogeneity, an …
known that MM tumor cells display extensive intratumoral genetic heterogeneity, an …
High expression of endoplasmic reticulum chaperone grp94 is a novel molecular hallmark of malignant plasma cells in multiple myeloma
Background Multiple myeloma (MM) is a hematologic malignancy that is characterized by
the proliferation of abnormal bone marrow plasma cells (BMPC) and overproduction of …
the proliferation of abnormal bone marrow plasma cells (BMPC) and overproduction of …
Lymphoplasmacytic lymphoma with IgG or IgA paraprotein: A study of 29 cases including cases that can mimic plasma cell neoplasms
Lymphoplasmacytic lymphoma (LPL) with IgG or IgA paraprotein is rare and a subset of
cases can mimic a plasma cell neoplasm (PCN). We studied 29 such cases to explore their …
cases can mimic a plasma cell neoplasm (PCN). We studied 29 such cases to explore their …