Acute graft-versus-host disease (GVHD) is a common immune complication that can occur
after allogeneic haematopoietic cell transplantation (alloHCT). Acute GVHD is a major …

Inborn errors of immunity (IEI) are a group of rare heterogeneous diseases. Currently, more
than 400 monogenetic IEI have been identified and increasingly a genetic diagnosis can be …

For over two decades, the EBMT has updated recommendations on indications for
haematopoietic cell transplantation (HCT) practice based on clinical and scientific …

Autologous T cells engineered to express chimeric antigen receptor against the B cell
antigen CD19 (CAR19) are achieving marked leukemic remissions in early-phase trials but …

Allogeneic hematopoietic stem cell transplantation (HSCT) from an HLA-haploidentical
relative (haplo-HSCT) is a suitable option for children with acute leukemia (AL) either …

Primary immunodeficiencies (PID) are disorders that for the most part result from mutations
in genes involved in immune host defense and immunoregulation. These conditions are …

Allogeneic blood or bone-marrow transplantation (alloBMT) is a potentially curative
treatment for a variety of haematological malignancies and nonmalignant diseases …

Haploidentical donors are now increasingly considered for transplantation in the absence of
HLA-matched donors or when an urgent transplant is needed. Donor-specific anti-HLA …

Hematopoietic stem-cell transplantation, which is used to treat both malignant and
nonmalignant conditions, was first conceived more than 50 years ago, but problems …

Objectives: Describe the indications for hematopoietic stem cell transplants. Review the
contraindications to hematopoietic stem cell transplants. Outline the potential complications …