Most of the anticancer chemotherapeutic drugs that are broadly and successfully used today
are DNA-damaging agents. Targeting of DNA has been proven to cause relatively potent …

Publisher Summary Calmodulin is the major intracellular, and intramembrane, Ca 2+
receptor. Its function is to detect free Ca 2+ and translate changes in Ca 2+ concentrations …

Some calcium antagonists and calmodulin inhibitors enhance the intracellular levels of
vincristine and Adriamycin in vincristine-and Adriamycin-resistant P388 leukemia cells by …

Use your knowledge of pharmacology to enhance oral care! Pharmacology and
Therapeutics for Dentistry, 6th Edition describes how to evaluate a patient's health and …

A tenet of biochemical pharmacology is that the pharmacological effects of drugs are
ultimately explainable by discrete biochemical actions. The caveat, of course, is that a …

The pathogenic yeast Candida albicans, a member of the mucosal microbiota, is
responsible for a large spectrum of infections, ranging from benign thrush and vulvovaginitis …

Atabrine has been available for nearly 60 years. It has a variety of actions and has been
administered to millions of individuals. Its antirheumatic properties have been well …

The cAMP signalling pathway has emerged as a key regulator of haematopoietic cell
proliferation, differentiation and apoptosis. In parallel, general understanding of the biology …

Calmodulin is a ubiquitous, calcium-binding protein that is responsible for many of the
intracellular actions of calcium. Recent evidence suggests that calmodulin may regulate …

A variety of reagents (local anesthetics, phenothiazines, ruthenium red, ryanodine,
dicyclohexylcarbodiimide, R 24571) inhibit Ca2+-induced Ca2+ release from purified canine …