Engineering organoids

M Hofer, MP Lutolf - Nature Reviews Materials, 2021 - nature.com
Organoids are in vitro miniaturized and simplified model systems of organs that have gained
enormous interest for modelling tissue development and disease, and for personalized …

Cell-based biosensors: Recent trends, challenges and future perspectives

N Gupta, V Renugopalakrishnan, D Liepmann… - Biosensors and …, 2019 - Elsevier
Existing at the interface of biology and electronics, living cells have been in use as
biorecognition elements (bioreceptors) in biosensors since the early 1970s. They are an …

Organ-on-a-chip: A new tool for in vitro research

J Yan, Z Li, J Guo, S Liu, J Guo - Biosensors and Bioelectronics, 2022 - Elsevier
Abstract Organ-on-a-chip (OOC, organ chip) technology can closely simulate the human
microenvironment, synthesize organ-like functional units on a fluidic chip substrate, and …

Advancement of sensor integrated organ-on-chip devices

GA Clarke, BX Hartse, AE Niaraki Asli, M Taghavimehr… - Sensors, 2021 - mdpi.com
Organ-on-chip devices have provided the pharmaceutical and tissue engineering worlds
much hope since they arrived and began to grow in sophistication. However, limitations for …

Integrating biosensors in organs-on-chip devices: A perspective on current strategies to monitor microphysiological systems

E Ferrari, C Palma, S Vesentini, P Occhetta, M Rasponi - Biosensors, 2020 - mdpi.com
Organs-on-chip (OoC), often referred to as microphysiological systems (MPS), are advanced
in vitro tools able to replicate essential functions of human organs. Owing to their …

Living anisotropic structural color hydrogels for cardiotoxicity screening

D Xu, Y Wang, L Sun, Z Luo, Y Luo, Y Wang, Y Zhao - ACS nano, 2023 - ACS Publications
Environmental toxins can result in serious and fatal damage in the human heart, while the
development of a viable stratagem for assessing the effects of environmental toxins on …

Drug toxicity evaluation based on organ-on-a-chip technology: a review

Y Cong, X Han, Y Wang, Z Chen, Y Lu, T Liu, Z Wu… - Micromachines, 2020 - mdpi.com
Organ-on-a-chip academic research is in its blossom. Drug toxicity evaluation is a promising
area in which organ-on-a-chip technology can apply. A unique advantage of organ-on-a …

Microengineered platforms for characterizing the contractile function of in vitro cardiac models

W Dou, M Malhi, Q Zhao, L Wang, Z Huang… - Microsystems & …, 2022 - nature.com
Emerging heart-on-a-chip platforms are promising approaches to establish cardiac
cell/tissue models in vitro for research on cardiac physiology, disease modeling and drug …

Conductive polymer‐based bioelectronic platforms toward sustainable and biointegrated devices: a journey from skin to brain across human body interfaces

O Bettucci, GM Matrone… - Advanced Materials …, 2022 - Wiley Online Library
Over the last few years, organic bioelectronics has experienced an exponential growth with
applications encompassing platforms for tissue engineering, drug delivery systems …

Tissue engineering and regenerative medicine 2019: the role of biofabrication—a year in review

T Ramos, L Moroni - Tissue Engineering Part C: Methods, 2020 - liebertpub.com
Despite its relative youth, biofabrication is unceasingly expanding by assimilating the
contributions from various disciplinary areas and their technological advances. Those …