[HTML][HTML] Can MRI measure myelin? Systematic review, qualitative assessment, and meta-analysis of studies validating microstructural imaging with myelin histology

A Lazari, I Lipp - Neuroimage, 2021 - Elsevier
Recent years have seen an increased understanding of the importance of myelination in
healthy brain function and neuropsychiatric diseases. Non-invasive microstructural magnetic …

Promise and pitfalls of g-ratio estimation with MRI

JSW Campbell, IR Leppert, S Narayanan, M Boudreau… - Neuroimage, 2018 - Elsevier
The fiber g-ratio is the ratio of the inner to the outer diameter of the myelin sheath of a
myelinated axon. It has a limited dynamic range in healthy white matter, as it is optimized for …

AxonDeepSeg: automatic axon and myelin segmentation from microscopy data using convolutional neural networks

A Zaimi, M Wabartha, V Herman, PL Antonsanti… - Scientific reports, 2018 - nature.com
Segmentation of axon and myelin from microscopy images of the nervous system provides
useful quantitative information about the tissue microstructure, such as axon density and …

Tutorial: a computational framework for the design and optimization of peripheral neural interfaces

S Romeni, G Valle, A Mazzoni, S Micera - Nature Protocols, 2020 - nature.com
Peripheral neural interfaces have been successfully used in the recent past to restore
sensory-motor functions in disabled subjects and for the neuromodulation of the autonomic …

TREM2‐dependent microglial function is essential for remyelination and subsequent neuroprotection

Y Wang, RV Kyauk, YAA Shen, L Xie, M Reichelt, H Lin… - Glia, 2023 - Wiley Online Library
Disability in multiple sclerosis (MS) is driven in part by the failure of remyelination and
progressive neurodegeneration. Microglia, and specifically triggering receptor expressed on …

MyelTracer: a semi-automated software for myelin g-ratio quantification

T Kaiser, HM Allen, O Kwon, B Barak, J Wang, Z He… - eneuro, 2021 - eneuro.org
In the central and peripheral nervous systems, the myelin sheath promotes neuronal signal
transduction. The thickness of the myelin sheath changes during development and in …

Axon and myelin morphology in animal and human spinal cord

A Saliani, B Perraud, T Duval, N Stikov… - Frontiers in …, 2017 - frontiersin.org
Characterizing precisely the microstructure of axons, their density, size and myelination is of
interest for the neuroscientific community, for example to help maximize the outcome of …

Multiple uses of fibrin sealant for nervous system treatment following injury and disease

NP Biscola, LP Cartarozzi, S Ulian-Benitez… - Journal of Venomous …, 2017 - SciELO Brasil
Lesions to the nervous system often produce hemorrhage and tissue loss that are difficult, if
not impossible, to repair. Therefore, scar formation, inflammation and cavitation take place …

Developmental origin of oligodendrocytes determines their function in the adult brain

S Foerster, EM Floriddia, D van Bruggen… - Nature …, 2024 - nature.com
In the mouse embryonic forebrain, developmentally distinct oligodendrocyte progenitor cell
populations and their progeny, oligodendrocytes, emerge from three distinct regions in a …

High-throughput segmentation of unmyelinated axons by deep learning

E Plebani, NP Biscola, LA Havton, B Rajwa… - Scientific Reports, 2022 - nature.com
Axonal characterizations of connectomes in healthy and disease phenotypes are
surprisingly incomplete and biased because unmyelinated axons, the most prevalent type of …