[HTML][HTML] Can MRI measure myelin? Systematic review, qualitative assessment, and meta-analysis of studies validating microstructural imaging with myelin histology
Recent years have seen an increased understanding of the importance of myelination in
healthy brain function and neuropsychiatric diseases. Non-invasive microstructural magnetic …
healthy brain function and neuropsychiatric diseases. Non-invasive microstructural magnetic …
Promise and pitfalls of g-ratio estimation with MRI
The fiber g-ratio is the ratio of the inner to the outer diameter of the myelin sheath of a
myelinated axon. It has a limited dynamic range in healthy white matter, as it is optimized for …
myelinated axon. It has a limited dynamic range in healthy white matter, as it is optimized for …
AxonDeepSeg: automatic axon and myelin segmentation from microscopy data using convolutional neural networks
A Zaimi, M Wabartha, V Herman, PL Antonsanti… - Scientific reports, 2018 - nature.com
Segmentation of axon and myelin from microscopy images of the nervous system provides
useful quantitative information about the tissue microstructure, such as axon density and …
useful quantitative information about the tissue microstructure, such as axon density and …
Tutorial: a computational framework for the design and optimization of peripheral neural interfaces
Peripheral neural interfaces have been successfully used in the recent past to restore
sensory-motor functions in disabled subjects and for the neuromodulation of the autonomic …
sensory-motor functions in disabled subjects and for the neuromodulation of the autonomic …
TREM2‐dependent microglial function is essential for remyelination and subsequent neuroprotection
Y Wang, RV Kyauk, YAA Shen, L Xie, M Reichelt, H Lin… - Glia, 2023 - Wiley Online Library
Disability in multiple sclerosis (MS) is driven in part by the failure of remyelination and
progressive neurodegeneration. Microglia, and specifically triggering receptor expressed on …
progressive neurodegeneration. Microglia, and specifically triggering receptor expressed on …
MyelTracer: a semi-automated software for myelin g-ratio quantification
In the central and peripheral nervous systems, the myelin sheath promotes neuronal signal
transduction. The thickness of the myelin sheath changes during development and in …
transduction. The thickness of the myelin sheath changes during development and in …
Axon and myelin morphology in animal and human spinal cord
Characterizing precisely the microstructure of axons, their density, size and myelination is of
interest for the neuroscientific community, for example to help maximize the outcome of …
interest for the neuroscientific community, for example to help maximize the outcome of …
Multiple uses of fibrin sealant for nervous system treatment following injury and disease
Lesions to the nervous system often produce hemorrhage and tissue loss that are difficult, if
not impossible, to repair. Therefore, scar formation, inflammation and cavitation take place …
not impossible, to repair. Therefore, scar formation, inflammation and cavitation take place …
Developmental origin of oligodendrocytes determines their function in the adult brain
S Foerster, EM Floriddia, D van Bruggen… - Nature …, 2024 - nature.com
In the mouse embryonic forebrain, developmentally distinct oligodendrocyte progenitor cell
populations and their progeny, oligodendrocytes, emerge from three distinct regions in a …
populations and their progeny, oligodendrocytes, emerge from three distinct regions in a …
High-throughput segmentation of unmyelinated axons by deep learning
Axonal characterizations of connectomes in healthy and disease phenotypes are
surprisingly incomplete and biased because unmyelinated axons, the most prevalent type of …
surprisingly incomplete and biased because unmyelinated axons, the most prevalent type of …