The immune-inflammatory response is associated with increased nitro-oxidative stress. The
aim of this mechanistic review is to examine:(a) the role of redox-sensitive transcription …

Atherosclerosis (AS) is a chronic inflammatory disease, involving a pathological process of
endothelial dysfunction, lipid deposition, plaque rupture, and arterial occlusion, and is one of …

Statins are commonly prescribed medications widely investigated for their potential actions
on the brain and mental health. Pre-clinical and clinical evidence suggests that statins may …

Background Major depression (MDD) and bipolar disorder (BD) are linked to immune
activation, increased oxidative stress, and lower antioxidant defenses. Objectives To …

Ethnopharmacological relevance Smilax china L., an extensively used traditional Chinese
medicine, is known as Baqia in China. It has been used to treat various inflammatory …

The endocannabinoid system (ECS) is composed of the endocannabinoid ligands
anandamide (AEA) and 2-arachidonoylgycerol (2-AG), their target cannabinoid receptors …

The endocannabinoid system (ECS) comprises two cognate endocannabinoid receptors
referred to as CB1R and CB2R. ECS dysregulation is apparent in neurodegenerative/neuro …

Endothelial damage is recognized as the initial step that precedes several cardiovascular
diseases (CVD), such as atherosclerosis, hypertension, and coronary artery disease. It has …

Abstract Statins (3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors) treat
dyslipidaemia and cardiovascular disease by inhibiting cholesterol biosynthesis. They also …

Cell death of endothelial cells (ECs) is a common devastating consequence of various
vascular-related diseases. Atherosclerosis, hypertension, sepsis, diabetes, cerebral …