Computational fluid dynamics (CFD) is a modeling technique that enables calculation of the
behavior of fluid flows in complex geometries. In cardiovascular medicine, CFD methods are …

The arterial wall is a composite material of elastin, collagen, and extracellular matrix with
acutely modifiable material properties through the action of smooth muscle cells. Therefore …

Simulation of haemodynamics has become increasingly popular within the research
community. Irrespective of the modelling approach (zero-dimensional (0D), one-dimensional …

The primary function of central arteries is to store elastic energy during systole and to use it
to sustain blood flow during diastole. Arterial stiffening compromises this normal mechanical …

Many vascular disorders, including aortic aneurysms and dissections, are characterized by
localized changes in wall composition and structure. Notwithstanding the importance of …

Although considered by many as the gold standard clinical measure of arterial stiffness,
carotid-to-femoral pulse wave velocity (cf-PWV) averages material and geometric properties …

Considerable insight into effectors of cardiovascular function can be gleaned from controlled
studies on mice, especially given the diverse models that are available. Toward this end …

Introduction: Aging has many effects on the cardiovascular system, including changes in
structure (aortic composition, and thus stiffening) and function (increased proximal blood …

Pulmonary arterial hypertension (PAH) is a disease characterized by an elevated pulmonary
arterial (PA) pressure. While several computational hemodynamic models of the pulmonary …

OBJECTIVES Aortic arch repair remains a major surgical challenge. Multiple manufacturers
are developing branched endografts for Zone 0 endovascular repair, extending the …