Sex disparities in COVID-19 severity and outcome: are men weaker or women stronger?

R Pivonello, RS Auriemma, C Pivonello, AM Isidori… - …, 2021 - karger.com
Abstract The coronavirus disease 2019 (COVID-19) outbreak, caused by severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2), is a global public health issue which has …

Sex differences in pharmacokinetics predict adverse drug reactions in women

I Zucker, BJ Prendergast - Biology of sex differences, 2020 - Springer
Background Women experience adverse drug reactions, ADRs, nearly twice as often as
men, yet the role of sex as a biological factor in the generation of ADRs is poorly understood …

Klinefelter syndrome, insulin resistance, metabolic syndrome, and diabetes: review of literature and clinical perspectives

A Salzano, R D'Assante, LM Heaney, F Monaco… - Endocrine, 2018 - Springer
Purpose Klinefelter syndrome (KS), the most frequent chromosomic abnormality in males, is
associated with hypergonadotropic hypogonadism and an increased risk of cardiovascular …

Differences in gastrointestinal safety profiles among novel oral anticoagulants: evidence from a network meta-analysis

WQ Guo, XH Chen, XY Tian, L Li - Clinical epidemiology, 2019 - Taylor & Francis
Background There is no consensus at present regarding the differences in the risk of GI
bleeding across various NOAC regimens. Therefore, we performed a network meta-analysis …

A systematic review of sex and gender differences in treatment outcome of inflammatory skin diseases: Is it time for new guidelines?

S Preis, S Ziehfreund, T Biedermann… - Journal of the …, 2024 - Wiley Online Library
Gender‐and sex‐specific differences in medicine were long‐time disregarded. Despite
numerous indications of gender‐and sex‐specific influences on the treatment of …

Sex differences in pharmacokinetics

I Zucker, BJ Prendergast - Sex and Gender Effects in Pharmacology, 2023 - Springer
Because women have been excluded from most clinical trials, assessment of sex differences
in pharmacokinetics is available for a minority of currently prescribed drugs. In a 2020 …

Biomarkers in pulmonary hypertension

AM Marra, E Bossone, A Salzano… - Heart failure …, 2018 - heartfailure.theclinics.com
The term biomarkers basically refers to humoral laboratory-measured molecules,“A
characteristic that is objectively measured and evaluated as an indicator of normal biological …

Corona virus disease 2019 (COVID-19) as a system-level infectious disease with distinct sex disparities

M Emadi-Baygi, M Ehsanifard… - Frontiers in …, 2021 - frontiersin.org
The current global pandemic of the Severe Acute Respiratory Syndrome CoronaVirus 2
(SARS-CoV-2) causing COVID-19, has infected millions of people and continues to pose a …

Biomarkers in heart failure: clinical insights

A Salzano, R D'Assante, MZ Israr… - Heart Failure …, 2021 - heartfailure.theclinics.com
Heart failure (HF) is a clinical syndrome caused by structural and/or functional cardiac
abnormalities and resulting from impaired cardiac output or an increase of intracardiac …

Growth hormone therapy in heart failure

A Salzano, AM Marra, R D'Assante… - Heart failure …, 2018 - heartfailure.theclinics.com
Despite considerable improvement in the management of heart failure (HF), unsustainable
levels of morbidity and mortality coupled with an increasing economic and social burden …