Abstract Each year, about 5–6 cases out of 100,000 people are diagnosed with primary
malignant brain tumors, of which about 80% are malignant gliomas (MGs). Glioblastoma …

Glioblastoma (GBM) is a highly malignant brain tumor characterized by a heterogeneous
population of genetically unstable and highly infiltrative cells that are resistant to …

Glioblastoma (GBM) is the most common type of adult malignant brain tumor, but its
molecular mechanisms are not well understood. In addition, the knowledge of the disease …

Glioblastoma (GBM) is the most lethal primary adult brain tumor and its pathology is
hallmarked by distorted neovascularization, diffuse tumor-associated macrophage …

In 2021 the World Health Organization published the fifth and latest version of the Central
Nervous System tumors classification, which incorporates and summarizes a long list of …

Glioblastoma multiforme (GBM), a WHO grade IV malignant glioma, is the most common and
lethal primary brain tumor in adults; few treatments are available. Median survival rates …

Background We conducted a phase II trial to evaluate the efficacy of dasatinib, a
multitargeted tyrosine kinase inhibitor, for adults with recurrent glioblastoma (GBM). Methods …

Background Patients with triple negative breast cancer (TNBC) exhibit poor prognosis and
are at high risk of tumour relapse, due to the resistance to chemotherapy. These aggressive …

Glioblastoma (GB) is one of the deadliest brain cancers to afflict humans, and it has a very
poor survival rate even with treatment. The extracellular adenosine-generating enzyme …

Simple Summary The biological pathways underlying glioblastoma malignancy and
radioresistance are still unclear. In this review, we describe the role of the hypoxic …