Fructose metabolism in the cerebellum

VA Funari, JE Crandall, DR Tolan - The Cerebellum, 2007 - Springer
Under normal physiological conditions, the brain utilizes only a small number of carbon
sources for energy. Recently, there is growing molecular and biochemical evidence that …

Early ultrastructural defects of axons and axon–glia junctions in mice lacking expression of Cnp1

JM Edgar, M McLaughlin, HB Werner, MC McCulloch… - Glia, 2009 - Wiley Online Library
Most axons in the central nervous system (CNS) are surrounded by a multilayered myelin
sheath that promotes fast, saltatory conduction of electrical impulses. By insulating the axon …

Versican V2 assembles the extracellular matrix surrounding the nodes of ranvier in the CNS

MT Dours-Zimmermann, K Maurer… - Journal of …, 2009 - Soc Neuroscience
The CNS-restricted versican splice-variant V2 is a large chondroitin sulfate proteoglycan
incorporated in the extracellular matrix surrounding myelinated fibers and particularly …

Glycogen function in adult central and peripheral nerves

RD Evans, AM Brown… - Journal of neuroscience …, 2013 - Wiley Online Library
We studied the roles of glycogen in axonal pathways of the central nervous system (CNS)
and peripheral nervous system (PNS). By using electrophysiological recordings, in …

Demyelination and axonal preservation in a transgenic mouse model of Pelizaeus‐Merzbacher disease

JM Edgar, MC McCulloch, P Montague… - EMBO molecular …, 2010 - embopress.org
It is widely thought that demyelination contributes to the degeneration of axons and, in
combination with acute inflammatory injury, is responsible for progressive axonal loss and …

Focal axonal swellings and associated ultrastructural changes attenuate conduction velocity in central nervous system axons: a computer modeling study

KV Kolaric, G Thomson, JM Edgar… - Physiological …, 2013 - Wiley Online Library
The constancy of action potential conduction in the central nervous system (CNS) relies on
uniform axon diameter coupled with fidelity of the overlying myelin providing high …

Fibre sub‐type specific conduction reveals metabolic function in mouse sciatic nerve

LR Rich, AM Brown - The journal of physiology, 2018 - Wiley Online Library
Key points We have developed an improved method that enables simultaneous recording of
stimulus evoked compound action potentials from large myelinated A fibres and small …

A novel approach for studying the physiology and pathophysiology of myelinated and non-myelinated axons in the CNS white matter

L Li, AA Velumian, M Samoilova, MG Fehlings - PLoS One, 2016 - journals.plos.org
Advances in brain connectomics set the need for detailed knowledge of functional properties
of myelinated and non-myelinated (if present) axons in specific white matter pathways. The …

Evidence That ITPR2-Mediated Intracellular Calcium Release in Oligodendrocytes Regulates the Development of Carbonic Anhydrase II + Type I/II Oligodendrocytes …

R Mei, L Huang, M Wu, C Jiang, A Yang… - Frontiers in Cellular …, 2021 - frontiersin.org
Myelination of neuronal axons in the central nervous system (CNS) by oligodendrocytes
(OLs) enables rapid saltatory conductance and axonal integrity, which are crucial for normal …

A non-linear regression analysis program for describing electrophysiological data with multiple functions using Microsoft Excel

AM Brown - Computer methods and programs in biomedicine, 2006 - Elsevier
The objective of this present study was to demonstrate a method for fitting complex
electrophysiological data with multiple functions using the SOLVER add-in of the ubiquitous …