Cell membrane deformation and bioeffects produced by tandem bubble-induced jetting flow

F Yuan, C Yang, P Zhong - Proceedings of the National …, 2015 - National Acad Sciences
Cavitation with bubble–bubble interaction is a fundamental feature in therapeutic
ultrasound. However, the causal relationships between bubble dynamics, associated flow …

Utilizing a structural mechanics approach to assess the primary effects of injury loads onto the axon and its components

A Montanino, S Kleiven - Frontiers in neurology, 2018 - frontiersin.org
Diffuse axonal injury (DAI) occurs as a result of the transmission of rapid dynamic loads from
the head to the brain and specifically to its neurons. Despite being one of the most common …

Effects of stretching speed on mechanical rupture of phospholipid/cholesterol bilayers: molecular dynamics simulation

T Shigematsu, K Koshiyama, S Wada - Scientific reports, 2015 - nature.com
Rupture of biological cell membrane under mechanical stresses is critical for cell viability. It
is triggered by local rearrangements of membrane molecules. We investigated the effects of …

[HTML][HTML] Mechanically induced integrin ligation mediates intracellular calcium signaling with single pulsating cavitation bubbles

F Li, TH Park, G Sankin, C Gilchrist, D Liao… - Theranostics, 2021 - ncbi.nlm.nih.gov
Therapeutic ultrasound or shockwave has shown its great potential to stimulate neural and
muscle tissue, where cavitation microbubble induced Ca 2+ signaling is believed to play an …

Single cell hydrodynamic stretching and microsieve filtration reveal genetic, phenotypic and treatment-related links to cellular deformability

F Li, I Cima, JH Vo, MH Tan, CD Ohl - Micromachines, 2020 - mdpi.com
Deformability is shown to correlate with the invasiveness and metastasis of cancer cells.
Recent studies suggest epithelial-to-mesenchymal transition (EMT) might enable cancer …

Stretch-induced interdigitation of a phospholipid/cholesterol bilayer

T Shigematsu, K Koshiyama… - The Journal of Physical …, 2018 - ACS Publications
The interdigitated gel (LβI) phase is one of the membrane phases of phospholipid molecules
in which the hydrophobic tails of the phospholipid molecules penetrate the opposite leaflet …

[PDF][PDF] Effect of membrane tension and pre-pore line tension on antimicrobial peptide PGLa-induced pore formation

M Ahmed - 2024 - shizuoka.repo.nii.ac.jp
An antimicrobial peptide (AMP), PGLa, has bactericidal activity. A recent study using single-
cell analysis demonstrates that a short time interaction of PGLa with single Escherichia coli …

[PDF][PDF] membrane deformation and bioeffects produced by tandem bubble-induced

F Yuan, C Yang, P Zhong - hadlandimaging.com
Cavitation with bubble–bubble interaction is a fundamental feature in therapeutic
ultrasound. However, the causal relationships between bubble dynamics, associated flow …

[PDF][PDF] Molecular Dynamics Study of Cholesterol Effects

重松, 大輝 - 2015 - ir.library.osaka-u.ac.jp
Cholesterol is one of the most essential molecule in phospholipid bilayers of animal cell
membranes and is known to help to maintain the bilayer integrity under mechanical stresses …

Interaction of transient fast flows with biological cells in microfluidic confinement

F Li - 2014 - dr.ntu.edu.sg
This thesis deals with the interaction of biological cells with transient fast flows mainly from
bubbles in microfluidic confinement. These interactions can be utilized to stretch and porate …