Olfactory dysfunction in neurodegenerative diseases

C Marin, D Vilas, C Langdon, I Alobid… - Current allergy and …, 2018 - Springer
Abstract Purpose of Review The sense of smell is today one of the focuses of interest in
aging and neurodegenerative disease research. In several neurodegenerative diseases …

Plant volatiles: production, function and pharmacology

ME Maffei, J Gertsch, G Appendino - Natural product reports, 2011 - pubs.rsc.org
Covering: 1989 to February 2011 Plant volatiles typically occur as a complex mixture of low-
molecular weight lipophilic compounds derived from different biosynthetic pathways, and …

All in a sniff: olfaction as a model for active sensing

M Wachowiak - Neuron, 2011 - cell.com
Sensation is an active process involving the sampling and central processing of external
stimuli selectively in space and time. Olfaction in particular depends strongly on active …

COVID-19 and olfactory dysfunction: a looming wave of dementia?

LM Kay - Journal of neurophysiology, 2022 - journals.physiology.org
Olfactory dysfunction is a hallmark symptom of COVID-19 disease resulting from the SARS-
CoV-2 virus. The cause of the sudden and usually temporary anosmia that most people …

Recent advances in the pathology of prodromal non-motor symptoms olfactory deficit and depression in Parkinson's disease: clues to early diagnosis and effective …

Y Bang, J Lim, HJ Choi - Archives of pharmacal research, 2021 - Springer
Parkinson's disease (PD) is a progressive neurodegenerative disease characterized by
movement dysfunction due to selective degeneration of dopaminergic neurons in the …

Balancing the robustness and efficiency of odor representations during learning

MW Chu, WL Li, T Komiyama - Neuron, 2016 - cell.com
For reliable stimulus identification, sensory codes have to be robust by including
redundancy to combat noise, but redundancy sacrifices coding efficiency. To address how …

Adult-born neurons facilitate olfactory bulb pattern separation during task engagement

WL Li, MW Chu, A Wu, Y Suzuki, I Imayoshi… - elife, 2018 - elifesciences.org
The rodent olfactory bulb incorporates thousands of newly generated inhibitory neurons
daily throughout adulthood, but the role of adult neurogenesis in olfactory processing is not …

Cholinergic inputs from Basal forebrain add an excitatory bias to odor coding in the olfactory bulb

M Rothermel, RM Carey, A Puche… - Journal of …, 2014 - Soc Neuroscience
Cholinergic modulation of central circuits is associated with active sensation, attention, and
learning, yet the neural circuits and temporal dynamics underlying cholinergic effects on …

Extrinsic neuromodulation in the rodent olfactory bulb

D Brunert, M Rothermel - Cell and Tissue Research, 2021 - Springer
Evolutionarily, olfaction is one of the oldest senses and pivotal for an individual's health and
survival. The olfactory bulb (OB), as the first olfactory relay station in the brain, is known to …

Optogenetic activation of basal forebrain cholinergic neurons modulates neuronal excitability and sensory responses in the main olfactory bulb

M Ma, M Luo - Journal of Neuroscience, 2012 - Soc Neuroscience
The main olfactory bulb (MOB) in mammals receives massive centrifugal input from
cholinergic neurons in the horizontal limb of the diagonal band of Broca (HDB) in the basal …