The precise functional role of the hippocampus remains a topic of much debate. The
dominant view is that the dorsal (or posterior) hippocampus is implicated in memory and …

After more than 100 years of research, the neuropathology of schizophrenia remains
unknown and this is despite the fact that both: Kraepelin, E., 1919/1971. Dementia praecox …

This review critically summarizes the neuropathology and genetics of schizophrenia, the
relationship between them, and speculates on their functional convergence. The …

Despite a hundred years' research, the neuropathology of schizophrenia remains obscure.
However, neither can the null hypothesis be sustained—that it is afunctional'psychosis, a …

David A. Lewis*‡ and Jeffrey A. Lieberman†‡* Departments of Psychiatry and Neuroscience
University of Pittsburgh School of Medicine this syndrome is increased as well. Recently …

This paper puts the case for the hippocampus as being central to the neuropathology and
pathophysiology of schizophrenia. The evidence comes from a range of approaches, both in …

The principle omega-3 fatty acid in brain, docosahexaenoic acid (DHA), accumulates in the
brain during perinatal cortical expansion and maturation. Animal studies have demonstrated …

This study tests the hypothesis that nicotinic cholinergic receptors, including those sensitive
to the antagonist α-bungarotoxin, are decreased in the hippocampus of schizophrenics. The …

Neuropathological studies have demonstrated deficits of GABAergic interneurons in the
hippocampus in schizophrenia, and selective deficits in some GABAergic sub-populations …

Schizophrenia is a debilitating mental illness that affects 1% of the population. Despite
intensive study, its molecular etiology remains enigmatic. Like many common diseases …