The blood brain barrier (BBB) plays a critically important role in the regulation of central
nervous system (CNS) homeostasis, but also represents a major limitation to treatments of …

Blood-brain barrier (BBB) remains a significant obstacle to drug therapy for brain diseases.
Focused ultrasound (FUS) combined with microbubbles (MBs) can locally and transiently …

Glioblastoma is the most aggressive primary brain tumor with a poor prognosis. The 2021
WHO CNS5 classification has further stressed the importance of molecular signatures in …

The blood–brain barrier (BBB) is a highly regulated physical and functional boundary that
tightly controls the transport of materials between the blood and the brain. There is an …

Simple Summary Glioblastoma (GBM) is a common primary brain tumor with a short median
overall survival despite aggressive treatment with resection, chemotherapy, and radiation …

Purpose Six years ago, in 2015, the Focused Ultrasound Foundation sponsored a workshop
to discuss, and subsequently transition the landscape, of focused ultrasound as a new …

Survival outcomes for patients with glioblastoma multiforme (GBM) have remained poor for
the past 15 years, reflecting a clear challenge in the development of more effective treatment …

Various surgical techniques and pharmaceutical treatments have been developed to
improve the current technologies of treating brain diseases. Focused ultrasound (FUS) is a …

Sonobiopsy is an emerging technology that combines focused ultrasound (FUS) with
microbubbles to enrich circulating brain disease-specific biomarkers for noninvasive …

Background Temporary disruption of the blood-brain barrier (BBB) using pulsed ultrasound
leads to the clearance of both amyloid and tau from the brain, increased neurogenesis, and …