Receptor-binding domain-specific human neutralizing monoclonal antibodies against SARS-CoV and SARS-CoV-2
F Yu, R Xiang, X Deng, L Wang, Z Yu, S Tian… - … and Targeted Therapy, 2020 - nature.com
The outbreaks of severe acute respiratory syndrome (SARS) and Coronavirus Disease 2019
(COVID-19) caused by SARS-CoV and SARS-CoV-2, respectively, have posed severe …
(COVID-19) caused by SARS-CoV and SARS-CoV-2, respectively, have posed severe …
Antibodies and vaccines target RBD of SARS-CoV-2
L Min, Q Sun - Frontiers in Molecular Biosciences, 2021 - frontiersin.org
The novel human coronavirus, severe acute respiratory syndrome coronavirus-2 (SARS-
CoV-2), which gives rise to the coronavirus disease 2019 (COVID-19), has caused a serious …
CoV-2), which gives rise to the coronavirus disease 2019 (COVID-19), has caused a serious …
Cross-neutralization of a SARS-CoV-2 antibody to a functionally conserved site is mediated by avidity
Most antibodies isolated from individuals with coronavirus disease 2019 (COVID-19) are
specific to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). However …
specific to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). However …
[HTML][HTML] High potency of a bivalent human VH domain in SARS-CoV-2 animal models
Novel COVID-19 therapeutics are urgently needed. We generated a phage-displayed
human antibody VH domain library from which we identified a high-affinity VH binder ab8 …
human antibody VH domain library from which we identified a high-affinity VH binder ab8 …
High neutralizing antibody titer in intensive care unit patients with COVID-19
ABSTRACT Coronavirus disease 2019 (COVID-19) has a wide spectrum of disease severity
from mild upper respiratory symptoms to respiratory failure. The role of neutralizing antibody …
from mild upper respiratory symptoms to respiratory failure. The role of neutralizing antibody …
[HTML][HTML] Longitudinal isolation of potent near-germline SARS-CoV-2-neutralizing antibodies from COVID-19 patients
C Kreer, M Zehner, T Weber, MS Ercanoglu… - Cell, 2020 - cell.com
The SARS-CoV-2 pandemic has unprecedented implications for public health, social life,
and the world economy. Because approved drugs and vaccines are limited or not available …
and the world economy. Because approved drugs and vaccines are limited or not available …
Structural insights into the cross-neutralization of SARS-CoV and SARS-CoV-2 by the human monoclonal antibody 47D11
The emergence of SARS-CoV-2 antibody escape mutations highlights the urgent need for
broadly neutralizing therapeutics. We previously identified a human monoclonal antibody …
broadly neutralizing therapeutics. We previously identified a human monoclonal antibody …
Nicotinic cholinergic system and COVID-19: In silico identification of interactions between α7 nicotinic acetylcholine receptor and the cryptic epitopes of SARS-Co-V …
SARS-CoV-2 is the coronavirus that originated in Wuhan in December 2019 and has spread
globally. Studies have shown that smokers are less likely to be diagnosed with or be …
globally. Studies have shown that smokers are less likely to be diagnosed with or be …
SARS-CoV-2 in animals: From potential hosts to animal models
A Michelitsch, K Wernike, L Ulrich… - Advances in Virus …, 2021 - Elsevier
Within only one year after the first detection of severe acute respiratory syndrome
coronavirus-2 (SARS-CoV-2), nearly 100 million infections were reported in the human …
coronavirus-2 (SARS-CoV-2), nearly 100 million infections were reported in the human …
Intranasal versus intratracheal exposure to lipopolysaccharides in a murine model of acute respiratory distress syndrome
F Khadangi, AS Forgues, S Tremblay-Pitre… - Scientific Reports, 2021 - nature.com
Due to frequent and often severe lung affections caused by COVID-19, murine models of
acute respiratory distress syndrome (ARDS) are increasingly used in experimental lung …
acute respiratory distress syndrome (ARDS) are increasingly used in experimental lung …