[HTML][HTML] The activity of ten natural extracts combined in a unique blend to maintain cholesterol homeostasis—in vitro model

S Ruga, R Galla, C Penna, C Molinari… - International Journal of …, 2022 - mdpi.com
Background: Hypercholesterolemia is a major cause of cardiovascular disease and statins,
the HMGCoA inhibitors, are the most prescribed drugs. Statins reduce the production of …

Inactivation of mitochondrial MUL1 E3 ubiquitin ligase deregulates mitophagy and prevents diet-induced obesity in mice

L Cilenti, J Di Gregorio, R Mahar, F Liu… - Frontiers in Molecular …, 2024 - frontiersin.org
Obesity is a growing epidemic affecting millions of people worldwide and a major risk factor
for a multitude of chronic diseases and premature mortality. Accumulating evidence …

Reversal of obesity development in Ceacam1−/− male mice by bone marrow transplantation or introduction of the human CEACAM1 gene

Z Zhang, D La Placa, G Gugiu, A Thunen, K Le… - …, 2022 - Wiley Online Library
Abstract Objective Although Ceacam1−/− male mice become obese on normal chow, the
effect of bone marrow transplantation or introduction of the carcinoembryonic antigen …

[HTML][HTML] Heart Uptake of [18F]Fluoro-4-Thia-Oleate in a Non-Alcoholic Fatty Liver Disease Mouse Model

J Li, W Hu, J Peng, P Wong, F Kandeel, T Olafsen… - Pharmaceuticals, 2022 - mdpi.com
The world-wide high incidence of non-alcoholic fatty liver disease (NAFLD) is of concern for
its progression to insulin resistance, steatohepatitis and cardiovascular disease (CVD). The …

Regulatory effect of caffeic acid phenethyl ester on oxidative stress and lipid metabolism in HepG2 cells.

C Liu, C Chang, R Chen, M Lin, R Sun, C Cai, H Cai… - 2023 - cabidigitallibrary.org
Caffeic acid phenethyl ester (CAPE), a natural polyphenol derived from propolis, has a good
regulatory effect on lipid metabolism, but its molecular mechanism is not clear. In the present …